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63岁时手部、膝盖和髋部骨关节炎超声特征的人群患病率:纽卡斯尔千家庭出生队列研究

Population prevalence of ultrasound features of osteoarthritis in the hand, knee and hip at age 63 years: the Newcastle thousand families birth cohort.

作者信息

Abraham Ajay M, Pearce Mark S, Mann Kay D, Francis Roger M, Birrell Fraser

机构信息

Institute of Health & Society, Newcastle University, Newcastle upon Tyne NE1 4LP, UK.

出版信息

BMC Musculoskelet Disord. 2014 May 19;15:162. doi: 10.1186/1471-2474-15-162.

Abstract

BACKGROUND

Musculoskeletal ultrasound has been found to be more sensitive than radiographs in detecting osteophytes. Our objective was to measure the prevalence of features of osteoarthritis (OA), in the dominant hand, knees and hips using ultrasound, within the Newcastle Thousand Families birth cohort.

METHODS

Participants were aged 61-63 (mean 63) years. Knee images were scored for presence of osteophytes and effusion. Hip images were scored for the presence of osteophytes and femoral head abnormality. The first carpometacarpal joint, metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints of the index finger (dominant hand) were imaged for osteophytes.

RESULTS

Among 311 participants, prevalence of osteophytes at the distal interphalangeal joint was 70% while it was 23%, 10% and 41% for index proximal interphalangeal and metacarpophalangeal and thumb base carpometacarpal joints respectively. Prevalence of knee osteophytes was 30%, hip OA was 41%. Prevalence of knee effusions was 24% (right) and 20% (left). Ultrasound evidence of generalised OA (48%) and isolated hand OA (31%) was common, compared to isolated hip or knee OA (5%) and both hip and knee OA (3%).

CONCLUSION

This is the first study to assess prevalence of ultrasound features of OA in a population-based sample. The higher prevalence of hand/hip OA, when compared to previous radiographic studies, supports the hypothesis that ultrasound is more sensitive than radiography in detecting OA, particularly for osteophytes.

摘要

背景

已发现肌肉骨骼超声在检测骨赘方面比X光片更敏感。我们的目标是在纽卡斯尔千户家庭出生队列中,使用超声测量优势手、膝盖和臀部骨关节炎(OA)特征的患病率。

方法

参与者年龄在61 - 63岁(平均63岁)。对膝盖图像进行骨赘和积液情况评分。对臀部图像进行骨赘和股骨头异常情况评分。对优势手食指的第一掌指关节、掌指关节、近端指间关节和远端指间关节进行骨赘成像。

结果

在311名参与者中,远端指间关节骨赘的患病率为70%,而食指近端指间关节、掌指关节和拇指基部掌指关节的患病率分别为23%、10%和41%。膝盖骨赘的患病率为30%,髋骨关节炎为41%。膝盖积液的患病率为24%(右侧)和20%(左侧)。与孤立性髋或膝骨关节炎(5%)以及髋和膝均患骨关节炎(3%)相比,全身性骨关节炎(48%)和孤立性手部骨关节炎(31%)的超声证据较为常见。

结论

这是第一项评估基于人群样本中骨关节炎超声特征患病率的研究。与先前的X光片研究相比,手/髋骨关节炎的较高患病率支持了超声在检测骨关节炎方面比X光片更敏感这一假设,尤其是在检测骨赘方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4fc/4031490/d37442730f93/1471-2474-15-162-1.jpg

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