Freeman Roy
Continuum (Minneap Minn). 2020 Feb;26(1):58-71. doi: 10.1212/CON.0000000000000825.
This article provides a summary of the autonomic neuropathies, including neuropathies associated with diabetes mellitus, neuropathies due to amyloid deposition, immune-mediated autonomic neuropathies (including those associated with a paraneoplastic syndrome), inherited autonomic neuropathies, and toxic autonomic neuropathies. The presenting features, diagnostic investigations, and natural history of these neuropathies are discussed.
Recent findings in autonomic peripheral neuropathy include data on the epidemiology and atypical presentations of diabetic autonomic neuropathy, treatment-induced neuropathy of diabetes mellitus, the presentation of immune-mediated neuropathies, and advances in hereditary neuropathy associated with amyloidosis and other hereditary neuropathies.
Knowledge and recognition of the clinical features of the autonomic neuropathies, combined with appropriate laboratory and electrophysiologic testing, will facilitate accurate diagnosis and management.
本文总结了自主神经病变，包括与糖尿病相关的神经病变、淀粉样蛋白沉积所致神经病变、免疫介导的自主神经病变（包括与副肿瘤综合征相关的神经病变）、遗传性自主神经病变以及中毒性自主神经病变。讨论了这些神经病变的临床表现、诊断检查及自然病程。
自主神经周围神经病变的最新发现包括糖尿病自主神经病变的流行病学和非典型表现数据、糖尿病治疗引起的神经病变、免疫介导神经病变的表现，以及与淀粉样变性相关的遗传性神经病变和其他遗传性神经病变的进展。
了解并认识自主神经病变的临床特征，结合适当的实验室和电生理检查，将有助于准确诊断和管理。
