Lacour J-P
Service de dermatologie, hôpital Archet 2, CHU de Nice, CS23079, 06202, Nice, Cedex 3, France.
Ann Dermatol Venereol. 2019 Dec;146(12S3):12S76-12S84. doi: 10.1016/S0151-9638(20)30017-X.
The treatment of atopic dermatitis is based on the use of topical steroids and emollients. When AD is resistant to a well-conducted topical treatment, phototherapy or systemic therapeutics can be used: ciclosporin, methotrexate, azathioprine or mycophenolate mofetil. However, the therapeutic landscape of AD is changing dramatically because of the approval of dupilumab (an anti-IL4/IL13 biologic therapy) and the possible future arrival of other biologicals (anti-IL13, anti-IL31…), and JAK inhibitors. © 2019 Elsevier Masson SAS. All rights reserved.
特应性皮炎的治疗基于局部使用类固醇和润肤剂。当特应性皮炎对规范的局部治疗耐药时,可采用光疗或全身治疗:环孢素、甲氨蝶呤、硫唑嘌呤或霉酚酸酯。然而,由于度普利尤单抗(一种抗IL4/IL13生物疗法)的获批以及未来可能出现的其他生物制剂(抗IL13、抗IL31……)和JAK抑制剂,特应性皮炎的治疗格局正在发生巨大变化。© 2019爱思唯尔马松出版社。保留所有权利。