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作者信息

Darrigade A-S

机构信息

Service de dermatologie, CHU Bordeaux, 1, rue Jean-Burguet, 33000, Bordeaux, France.

出版信息

Ann Dermatol Venereol. 2019 Dec;146(12S3):12S85-12S95. doi: 10.1016/S0151-9638(20)30018-1.

DOI:10.1016/S0151-9638(20)30018-1

PMID:31997737

Abstract

Atopic dermatitis is a chronic disease with an alteration of the skin barrier and an abnormal immune response. The European guidelines for treatment of atopic dermatitis in children and adults recommend basic hygiene rules including daily use of emollient. Then in the first therapeutic line, for mild or acute atopic dermatitis, the prescription of local care by topical corticosteroids or topical calcineurin inhibitors is recommended. A proactive treatment is now recommended. If the atopic dermatitis is moderate or recurrent, the use of phototherapy in addition to topical treatment is recommended. Each therapeutic step can be added to improve the lesions and reduce the burden of the disease on the patient's daily life. © 2019 Elsevier Masson SAS. All rights reserved.

摘要

特应性皮炎是一种伴有皮肤屏障改变和异常免疫反应的慢性疾病。欧洲儿童和成人特应性皮炎治疗指南推荐了基本的卫生规则，包括每日使用润肤剂。在一线治疗中，对于轻度或急性特应性皮炎，建议外用糖皮质激素或外用钙调神经磷酸酶抑制剂进行局部护理。现在推荐进行积极治疗。如果特应性皮炎为中度或复发性，建议在局部治疗的基础上使用光疗。每个治疗步骤都可叠加使用，以改善皮损并减轻疾病对患者日常生活的负担。© 2019爱思唯尔马松出版社。保留所有权利。