Huang Yan, Xu Lu, Kuang Li, Wang Wo, Cao Jun, Xiao Mu-Ni
GCP Office, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Chongqing Medical and Pharmaceutical College, Chongqing, China.
Neural Regen Res. 2020 Aug;15(8):1554-1559. doi: 10.4103/1673-5374.274346.
Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents. However, whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown. This observational cross-sectional study enrolled 41 young Internet addicts, aged from 15 to 20 years, from the Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, China from January to May 2018. The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history. Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner. The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group. In the resting state, the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities, which may provide a new basis for studying suicide pathogenesis in Internet addicts. The study was authorized by the Ethics Committee of Chongqing Medical University, China (approval No. 2017 Scientific Research Ethics (2017-157)) on December 11, 2017.
网络成瘾与青少年自杀行为风险增加相关，且可能导致大脑功能障碍。然而，有自杀企图的网络成瘾青少年是否会出现大脑功能障碍仍不清楚。这项观察性横断面研究于2018年1月至5月从中国重庆医科大学附属第一医院精神科招募了41名年龄在15至20岁之间的年轻网络成瘾者。参与者包括21名有自杀企图的个体和20名无自杀企图史的网络成瘾个体。通过3.0T磁共振成像扫描仪获取静息状态下的脑图像。结果显示，与无自杀企图组相比，有自杀企图组右侧三角部额下回和右侧岛盖部的活动显著增加。在静息状态下，因网络成瘾而自杀未遂的青少年前额叶表现出功能异常，这可能为研究网络成瘾者自杀发病机制提供新的依据。该研究于2017年12月11日获得中国重庆医科大学伦理委员会批准（批准号：2017科研伦理(2017 - 157)）。
