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布瓦西埃氏植物的抗炎活性

Anti-inflammatory activity of Boiss.

作者信息

Demirkan Serkan, Özçınar Özge, Kıvçak Bijen

机构信息

Department of Dermatology and Venerology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

Department of Pharmacognosy, Faculty of Pharmacy, Ege University, İzmir, Turkey.

出版信息

Postepy Dermatol Alergol. 2019 Dec;36(6):677-680. doi: 10.5114/ada.2019.91417. Epub 2019 Dec 30.

Abstract

INTRODUCTION

Traditionally, genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several and studies that showed the pharmacological properties of species such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties.

AIM

Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of extracts.

MATERIAL AND METHODS

Five different extracts of were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); -hexane and sesquiterpene extracts of Bois showed significantly reduced erythema compared to the negative control.

RESULTS

Only -hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect.

CONCLUSIONS

This is the first report on anti-inflammatory activity of and we showed an anti-inflammatory effect of -hexane and sesquiterpene extract of with UV erythema test as a result, hence extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity.

摘要

引言

在欧洲,传统上[属名]一直被用于治疗胃肠道疾病、痔疮和胃痛。有多项研究表明该属植物具有抗菌、抗炎、抗水肿和保肝等药理特性。

目的

我们的研究采用大鼠炎症模型,旨在评估[植物名]提取物的抗炎特性。

材料与方法

测试了[植物名]的五种不同提取物,并与阴性对照以及两种不同的外用皮质类固醇(倍他米松和氢化可的松)进行比较;[植物名]的正己烷和倍半萜提取物与阴性对照相比,红斑明显减轻。

结果

只有[植物名]的正己烷和倍半萜提取物具有抗炎作用。

结论

这是关于[植物名]抗炎活性的首次报道,通过紫外线红斑试验,我们证明了[植物名]的正己烷和倍半萜提取物具有抗炎作用,因此,由于其抗炎活性,[植物名]提取物可用于治疗炎症性皮肤病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/511a/6986279/9722858bf58c/PDIA-36-91417-g001.jpg

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