Regional Department for Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital, P.O. Box 4956, Nydalen, N-0424, Oslo, Norway.
Specialized out-patient unit for OCD-spectrum Disorders, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
BMC Psychiatry. 2020 Jan 30;20(1):36. doi: 10.1186/s12888-020-2457-0.
Obsessive-compulsive disorder (OCD) is common in patients with eating disorders (EDs). There is a lack of research investigating the presence of ED symptoms among patients with OCD, despite concerns that many of these patients may be at high risk for EDs. Our objective was to assess the presence of ED symptoms in patients receiving treatment for OCD.
Adult patients with OCD (n = 132, 71% females) and controls (n = 260, 90% females) completed the Eating Disorder Examination-Questionnaire (EDE-Q) at admission to a specialized OCD outpatient unit. A small subset of patients (n = 22) also completed the EDE-Q 3-months after end of treatment.
At the group-level, mean EDE-Q scores did not differ significantly between female patients and controls. However, female patients compared to controls were significantly more likely to score above the EDE-Q cut-off (23% vs. 11%) and have a probable ED (9% vs. 1%), indicating elevated rates of ED symptoms in the clinical range. There was no evidence of elevated rates of ED symptoms in male patients, though sample sizes were small. Preliminary follow-up data showed that certain ED symptoms improved significantly from admission to 3-month follow-up.
Our findings suggest that while ED symptoms are not generally elevated in female patients with OCD, a considerable subset of female patients may have a clinical ED or be at high risk of developing one. Clinicians should be alert to ED symptoms in female patients with OCD, and our findings raise the issue of whether ED screening of female patients with OCD is warranted.
强迫症（OCD）在饮食障碍（ED）患者中很常见。尽管许多此类患者可能存在 ED 的高风险，但针对 OCD 患者中 ED 症状的研究却很少。我们的目的是评估接受 OCD 治疗的患者中 ED 症状的存在情况。
132 名成年 OCD 患者（71%为女性）和 260 名对照者（90%为女性）在专门的 OCD 门诊接受治疗时，完成了饮食障碍检查问卷（EDE-Q）。一小部分患者（n=22）在治疗结束后 3 个月也完成了 EDE-Q。
在组水平上，女性患者与对照组的 EDE-Q 平均得分无显著差异。然而，与对照组相比，女性患者更有可能得分高于 EDE-Q 截断值（23%比 11%）和患有可能的 ED（9%比 1%），表明临床范围内 ED 症状的发生率较高。男性患者中没有发现 ED 症状发生率升高的证据，尽管样本量较小。初步随访数据显示，某些 ED 症状从入院到 3 个月随访时显著改善。
我们的研究结果表明，尽管 OCD 女性患者的 ED 症状通常不升高，但相当一部分女性患者可能存在临床 ED 或有发展为 ED 的高风险。临床医生应该警惕 OCD 女性患者的 ED 症状，我们的研究结果提出了 OCD 女性患者是否需要进行 ED 筛查的问题。
