Chung Soo Jie, Kim Byung-Keun, Oh Ji Hyun, Shim Ji-Su, Chang Yoon-Seok, Cho Sang-Heon, Yang Min-Suk
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Korea.
Allergy. 2020 Jul;75(7):1640-1648. doi: 10.1111/all.14212. Epub 2020 Feb 19.
The effect of novel tobacco products, such as electronic cigarettes (EC) and heated tobacco products (HTP), on allergic rhinitis (AR) and asthma is not well known.
To evaluate the health effect of novel tobacco products on asthma and AR.
This study was conducted using large survey data on Korean middle and high school students. The relationship between current asthma/AR and novel tobacco products user status was evaluated. In order to compare the combined effects of conventional cigarette (CC), EC, and HTP use on current allergic diseases, the participants were classified into 18 groups based on CC (current, former, and never), EC (current, former, and never), and HTP (ever and never) status.
A total of 60,040 participants representing 2,850,118 Korean adolescents were analyzed. Of all participants, 6.7%, 2.7%, and 2.9% were current CC, current EC, and ever HTP users, respectively. Current CC and ever HTP use was significantly associated with current asthma and AR in adjusted models. Current EC showed association with current AR but the association with asthma disappeared in the adjusted model. Among 18 groups, the groups including current CC use showed higher risk of current AR and asthma than never HTP-never EC-never CC group. The odds ratio of current asthma especially increased more in those who used EC and/or HTP with CC concurrently than those in the never HTP-never EC-current CC user group.
Using EC and/or HTP in adolescents might enhance the adverse effect of CC on AR and asthma.
新型烟草产品，如电子烟（EC）和加热烟草产品（HTP），对过敏性鼻炎（AR）和哮喘的影响尚不清楚。
评估新型烟草产品对哮喘和AR的健康影响。
本研究使用了关于韩国中学生的大型调查数据。评估了当前哮喘/AR与新型烟草产品使用状况之间的关系。为了比较传统香烟（CC）、电子烟和加热烟草产品使用对当前过敏性疾病的综合影响，根据CC（当前、曾经和从不）、电子烟（当前、曾经和从不）和加热烟草产品（曾经和从不）的使用状况将参与者分为18组。
共分析了代表2850118名韩国青少年的60040名参与者。在所有参与者中，当前使用CC、当前使用电子烟和曾经使用加热烟草产品的比例分别为6.7%、2.7%和2.9%。在调整模型中，当前使用CC和曾经使用加热烟草产品与当前哮喘和AR显著相关。当前使用电子烟与当前AR相关，但在调整模型中与哮喘的关联消失。在18组中，包括当前使用CC的组比从不使用加热烟草产品-从不使用电子烟-从不使用CC的组患当前AR和哮喘的风险更高。与从不使用加热烟草产品-从不使用电子烟-当前使用CC的用户组相比，同时使用电子烟和/或加热烟草产品与CC的人群中当前哮喘的优势比尤其增加得更多。
青少年使用电子烟和/或加热烟草产品可能会增强CC对AR和哮喘的不良影响。
