Department of Preventive Medicine and Public Health, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan
Department of Information and Computer Technology, Faculty of Engineering, Tokyo University of Science, Katushika-ku, Tokyo, Japan.
BMJ Open. 2023 Mar 7;13(3):e065322. doi: 10.1136/bmjopen-2022-065322.
To investigate the association between secondhand-aerosol exposure from heated tobacco products (HTPs) and respiratory symptoms among current non-smokers.
Cross-sectional study.
Internet survey conducted between 8 and 26 February 2021 in Japan.
Non-smoking respondents at the survey aged 15-80 years.
Self-reported secondhand-aerosol exposure.
We defined asthma/asthma-like symptoms as a primary outcome and persistent cough as a secondary outcome. We examined the association between secondhand-aerosol exposure from HTPs and respiratory symptoms (asthma attacks/asthma-like symptoms and persistent cough). The prevalence ratio (PR) and 95% CI were calculated by using weighted, multivariable 'modified' Poisson regression models.
Of the 18 839 current non-smokers, 9.8% (95% CI 8.2% to 11.7%) and 16.7% (95% CI 14.8% to 18.9%) of those who were exposed to secondhand aerosols reported asthma attacks/asthma-like symptoms and persistent cough, whereas 4.5% (95% CI 3.9% to 5.2%) and 9.6% (95% CI 8.4% to 11.0%) of those who were not, respectively. Secondhand-aerosol exposure was associated with respiratory symptoms (asthma attacks/asthma-like symptoms: PR 1.49, 95% CI 1.21 to 1.85; persistent cough: PR 1.44, 95% CI 1.21 to 1.72) after adjusting for covariates.
Secondhand-aerosol exposure from HTPs was associated with both asthma attacks/asthma-like symptoms and persistent cough. These results provide policymakers with meaningful information in the regulation of HTP use for the protection of current non-smokers.
研究加热烟草制品(HTP)二手气溶胶暴露与当前非吸烟者呼吸系统症状之间的关系。
横断面研究。
2021 年 2 月 8 日至 26 日在日本进行的互联网调查。
调查中年龄在 15 至 80 岁的非吸烟应答者。
自我报告的二手气溶胶暴露。
我们将哮喘/哮喘样症状定义为主要结局,将持续性咳嗽定义为次要结局。我们检查了 HTP 二手气溶胶暴露与呼吸系统症状(哮喘发作/哮喘样症状和持续性咳嗽)之间的关系。使用加权、多变量“修正”泊松回归模型计算患病率比(PR)和 95%置信区间。
在 18839 名当前非吸烟者中,暴露于二手气溶胶的人群报告哮喘发作/哮喘样症状和持续性咳嗽的比例分别为 9.8%(95%CI 8.2%至 11.7%)和 16.7%(95%CI 14.8%至 18.9%),而未暴露于二手气溶胶的人群报告哮喘发作/哮喘样症状和持续性咳嗽的比例分别为 4.5%(95%CI 3.9%至 5.2%)和 9.6%(95%CI 8.4%至 11.0%)。调整协变量后,二手气溶胶暴露与呼吸系统症状(哮喘发作/哮喘样症状:PR 1.49,95%CI 1.21 至 1.85;持续性咳嗽:PR 1.44,95%CI 1.21 至 1.72)相关。
HTP 二手气溶胶暴露与哮喘发作/哮喘样症状和持续性咳嗽均相关。这些结果为决策者在 HTP 使用监管方面提供了有意义的信息,以保护当前非吸烟者。