特发性间质性肺炎的病理学

Pathology of Idiopathic Interstitial Pneumonias.

作者信息

Zaizen Yoshiaki, Fukuoka Junya

机构信息

Department of Pathology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan; Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.

Department of Pathology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan; Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki 852-8501, Japan; Department of Pathology, Kameda Medical Center, 929 Higashi-machi, Kamogawa, Chiba 296-8602, Japan.

出版信息

Surg Pathol Clin. 2020 Mar;13(1):91-118. doi: 10.1016/j.path.2019.11.006. Epub 2019 Dec 24.

DOI:10.1016/j.path.2019.11.006

PMID:32005437

Abstract

This review discusses diagnostic pathology in idiopathic interstitial pneumonias (IIPs). Accurate understanding of basic structure of lung lobules is critical because the location of abnormalities inside the lobule is an important effector of pathology diagnosis. Depending on the method of obtaining tissue, recognition of the location may be difficult or impossible. Cryobiopsy is a new technology and its coverage of lung lobules is limited. This article discusses fundamental anatomy and approach to interstitial pneumonia. In addition, most histologic types of IIPs are covered, but the focus is on diagnosis of usual interstitial pneumonia because of its clinical importance.

摘要

本综述讨论特发性间质性肺炎（IIP）的诊断病理学。准确理解肺小叶的基本结构至关重要，因为小叶内异常的位置是病理诊断的重要依据。根据获取组织的方法，可能难以或无法识别位置。冷冻活检是一项新技术，其对肺小叶的覆盖范围有限。本文讨论间质性肺炎的基础解剖学和诊断方法。此外，涵盖了IIP的大多数组织学类型，但由于其临床重要性，重点是寻常型间质性肺炎的诊断。