Lynn W A, Marcus R E
Department of Medicine, Hillingdon Hospital, Middlesex, UK.
Postgrad Med J. 1988 May;64(751):395-7. doi: 10.1136/pgmj.64.751.395.
We report a case of focal sclerosing glomerulonephritis which developed 11 years after successful treatment of nodular sclerosing Hodgkin's disease. Hodgkin's disease relapsed 7 months later and responded completely to combination chemotherapy with simultaneous improvement in renal function. This case shows that relapse of Hodgkin's disease may occur after a 10 year interval and furthermore it may preceded by nephrotic syndrome. Renal disease in such cases may not recover until the underlying Hodgkin's disease is treated.
我们报告一例局灶性硬化性肾小球肾炎，该病例在结节性硬化型霍奇金病成功治疗11年后出现。7个月后霍奇金病复发，联合化疗后完全缓解，同时肾功能有所改善。该病例表明，霍奇金病可能在10年间隔后复发，而且可能先于肾病综合征出现。在此类病例中，直到潜在的霍奇金病得到治疗，肾脏疾病才可能恢复。
