From the Sir Salimullah Medical College (SSMC), Dhaka, Bangladesh.
Exp Clin Transplant. 2020 Jan;18(Suppl 1):64-67. doi: 10.6002/ect.TOND-TDTD2019.P11.
Health-related quality of life is increasingly used as an important measurement of treatment outcome. Here, quality of life parameters in renal transplant recipients were evaluated and compared with patients with chronic kidney disease on maintenance hemodialysis and with those who were not on dialysis.
This cross-sectional study included patients seen at a number of tertiary renal care hospitals (there were 15 renal transplant recipients, 20 patients on maintenance hemodialysis, and 28 patients with chronic kidney disease not on dialysis). Forty healthy individual were also included as the control group. Different biochemical parameters were analyzed. Quality of life was assessed with the KDQOL-SF-36 (version 1.3) questionnaire.
Mean age was 39 ± 11 for transplant patients, 43 ± 11 years for patients on hemodialysis, 49 ± 12 years for patients with chronic kidney disease not on dialysis, and 34 ± 11 years for the healthy control group. Distribution of sex was similar. Transplant recipients had higher quality of life scores, with some scores similar to healthy controls patients, like physical function (P = .85) and social function (P = .25). Scores were 100 ± 12, 69 ± 27, 37 ± 28, and 91 ± 10 (P < .001) for physical function; 94 ± 12, 44 ± 17, 30 ± 14, and 69 ± 29 (P < .001) for pain; 99 ± 11, 61 ± 46, 24 ± 15, and 70 ± 28 (P < .001) for social function; and 91 ± 11, 51 ± 13, 40 ± 7, and 66 ± 11 (P < .001) for energy/fatigue in healthy control, chronic kidney disease patients not on dialysis, hemodialysis patients, and transplant recipients, respectively.
Quality of life is poor in patients with chronic kidney disease. However, renal transplant can improve quality of life. Transplant patients showed many quality of life scores similar to healthy individuals.
健康相关生活质量日益被用作治疗结果的重要衡量标准。本研究评估了肾移植受者的生活质量参数，并与维持性血液透析的慢性肾脏病患者以及未透析的患者进行了比较。
这是一项横断面研究，纳入了多家三级肾脏护理医院的患者（包括 15 名肾移植受者、20 名维持性血液透析患者和 28 名未透析的慢性肾脏病患者）。还纳入了 40 名健康个体作为对照组。分析了不同的生化参数。使用 KDQOL-SF-36（版本 1.3）问卷评估生活质量。
移植患者的平均年龄为 39 ± 11 岁，血液透析患者为 43 ± 11 岁，未透析的慢性肾脏病患者为 49 ± 12 岁，健康对照组为 34 ± 11 岁。性别分布相似。移植受者的生活质量评分较高，有些评分与健康对照组相似，如身体功能（P =.85）和社会功能（P =.25）。身体功能的评分分别为 100 ± 12、69 ± 27、37 ± 28 和 91 ± 10（P <.001）；疼痛的评分分别为 94 ± 12、44 ± 17、30 ± 14 和 69 ± 29（P <.001）；社会功能的评分分别为 99 ± 11、61 ± 46、24 ± 15 和 70 ± 28（P <.001）；能量/疲劳的评分分别为 91 ± 11、51 ± 13、40 ± 7 和 66 ± 11（P <.001），分别为健康对照组、未透析的慢性肾脏病患者、血液透析患者和移植受者。
慢性肾脏病患者的生活质量较差。然而，肾移植可以改善生活质量。移植患者的许多生活质量评分与健康个体相似。
