Division of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Division of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Prev Med. 2020 May;58(5):703-706. doi: 10.1016/j.amepre.2019.11.008. Epub 2020 Jan 31.
With a rapid increase in prescription opioid overdose deaths and a proliferation of pain clinics in the mid-2000s, Florida emerged as an epicenter of the opioid overdose epidemic. In response, Florida implemented pain clinic laws and operationalized its Prescription Drug Monitoring Program. This study examines the effect of these policies on rates of inpatient stays and emergency department visits for opioid-related overdoses.
Using data from the 2008-2015 State Emergency Department Databases and State Inpatient Databases, quarterly rates of inpatient stays and emergency department visits for prescription opioid-related overdoses and heroin-related overdoses were computed. A comparative interrupted time series analysis examined the effect of these policies on opioid overdose rates. North Carolina served as a control state because it did not implement similar policies during the study period. The data were analyzed in 2019.
Compared with North Carolina, Florida's polices were associated with reductions in the rates of prescription opioid-related overdose inpatient stays and emergency department visits, a level reduction of 2.31 per 100,000 and a reduction in the trend of 0.16 per 100,000 population each quarter. The policies were associated with a reduction of 13,532 inpatient stays and emergency department visits for prescription opioid-related overdoses during the study period. No statistically significant association was found between the policies and heroin-related overdose inpatient stays and emergency department visits.
To address the opioid overdose epidemic, states have implemented policies such as Prescription Drug Monitoring Programs and pain clinic laws designed to reduce inappropriate opioid prescribing. Such laws may be effective in reducing prescription opioid-related overdoses.
随着 21 世纪中期处方类阿片类药物过量致死人数的迅速增加和疼痛诊所的激增，佛罗里达州成为阿片类药物过量流行的中心。作为回应，佛罗里达州实施了疼痛诊所法，并实施了其处方药物监测计划。本研究考察了这些政策对与阿片类药物相关的住院和急诊就诊率的影响。
使用 2008-2015 年州急诊数据库和州住院数据库的数据，计算了与处方类阿片相关的过量和海洛因相关的过量的住院和急诊就诊率。比较中断时间序列分析考察了这些政策对阿片类药物过量率的影响。北卡罗来纳州作为对照州，因为在研究期间没有实施类似的政策。数据在 2019 年进行了分析。
与北卡罗来纳州相比，佛罗里达州的政策与减少与处方类阿片相关的过量住院和急诊就诊率有关，每 10 万人减少 2.31 人，每季度减少 0.16 人。该政策与研究期间与处方类阿片相关的过量住院和急诊就诊减少了 13532 人次。政策与海洛因相关的过量住院和急诊就诊没有统计学上的显著关联。
为了解决阿片类药物过量流行问题，各州已实施了诸如处方药物监测计划和疼痛诊所法等政策，旨在减少不适当的阿片类药物处方。这些法律可能有效减少与处方类阿片相关的过量。
