Kennedy-Hendricks Alene, Richey Matthew, McGinty Emma E, Stuart Elizabeth A, Barry Colleen L, Webster Daniel W
Alene Kennedy-Hendricks, Emma E. McGinty, Elizabeth A. Stuart, Colleen L. Barry, and Daniel W. Webster are with the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD. Matthew Richey is with St. Olaf College, Northfield, MN.
Am J Public Health. 2016 Feb;106(2):291-7. doi: 10.2105/AJPH.2015.302953. Epub 2015 Dec 21.
We examined the effect on opioid overdose mortality of Florida state laws and law enforcement operations targeting "pill mills."
We collected 2003 to 2012 mortality data from the Florida Department of Health and the North Carolina State Center for Health Statistics (the comparison state) to estimate changes in the rates of death from prescription opioid, heroin, or any opioid overdose.
Florida's actions were associated with an estimated 1029 lives saved from prescription opioid overdose over a 34-month period. Estimated reductions in deaths grew over the intervention period, with rates per 100,000 population that were 0.6 lower in 2010, 1.8 lower in 2011, and 3.0 lower in 2012 than what would have been expected had the changes in mortality rate trends in Florida been the same as changes in trends in North Carolina. Florida's mortality rates from heroin and total opioid overdose were also lower than anticipated relative to changes in trends in North Carolina.
Findings from this study indicate that laws regulating pain clinics and enforcement of these laws may, in combination, reduce opioid overdose deaths.
我们研究了佛罗里达州针对“药丸磨坊”的州法律和执法行动对阿片类药物过量死亡率的影响。
我们收集了2003年至2012年佛罗里达州卫生部和北卡罗来纳州卫生统计中心(对照州)的死亡率数据,以估计处方阿片类药物、海洛因或任何阿片类药物过量死亡率的变化。
在34个月的时间里,佛罗里达州的行动估计挽救了1029条因处方阿片类药物过量而死亡的生命。在干预期间,估计的死亡人数减少有所增加,2010年每10万人口的死亡率比预期低0.6,2011年低1.8,2012年低3.0,前提是佛罗里达州的死亡率趋势变化与北卡罗来纳州的趋势变化相同。相对于北卡罗来纳州趋势的变化,佛罗里达州海洛因和阿片类药物总过量的死亡率也低于预期。
本研究结果表明,规范疼痛诊所的法律以及这些法律的执行可能共同降低阿片类药物过量死亡人数。