Davallow Ghajar Ladan, DeBoer Mark Daniel
Virginia Commonwealth University, Richmond, VA, USA.
University of Virginia, Charlottesville, VA, USA.
Clin Pediatr (Phila). 2020 May;59(4-5):401-410. doi: 10.1177/0009922820902437. Epub 2020 Feb 1.
Our objective was to evaluate the risk of short stature in children with attention-deficit/hyperactivity disorder (ADHD) and the effect of ADHD and its treatment on height-for-age score (HAZ) and body mass index-for-age score (BMIZ) in early childhood. We evaluated 7603 children from the Early Childhood Longitudinal Study-Kindergarten Cohort 2011 and found that children with ADHD had lower HAZ at second and fourth grades and lower BMIZ at K to fourth grade. Children with ADHD at fourth grade had almost 4 times higher odds of short stature. Children with ADHD at K grew at a slower rate from K to fourth grade (difference in ΔHAZ = 0.23, 95% confidence interval = 0.04-0.42) and had less gain in BMI (difference in ΔBMIZ = 0.16, 95% confidence interval = 0.03-0.29). Longer duration of ADHD medication use was associated with lower HAZ at fourth grade and slower growth from K to fourth grade. These data may assist pediatricians in considering risk of poor growth in children with ADHD.
我们的目标是评估注意力缺陷多动障碍（ADHD）患儿身材矮小的风险，以及ADHD及其治疗对幼儿期年龄别身高评分（HAZ）和年龄别体重指数评分（BMIZ）的影响。我们对来自2011年幼儿纵向研究 - 幼儿园队列的7603名儿童进行了评估，发现患有ADHD的儿童在二年级和四年级时HAZ较低，在幼儿园至四年级时BMIZ较低。四年级患有ADHD的儿童身材矮小的几率几乎高出4倍。幼儿园时患有ADHD的儿童从幼儿园到四年级的生长速度较慢（ΔHAZ差异 = 0.23，95%置信区间 = 0.04 - 0.42），BMI增加较少（ΔBMIZ差异 = 0.16，95%置信区间 = 0.03 - 0.29）。ADHD药物使用时间较长与四年级时较低的HAZ以及从幼儿园到四年级较慢的生长速度相关。这些数据可能有助于儿科医生考虑ADHD患儿生长发育不良的风险。
