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患有注意力缺陷/多动障碍的儿童在幼儿期生长发育迟缓及身材矮小的风险增加。

Children With Attention-Deficit/Hyperactivity Disorder Are at Increased Risk for Slowed Growth and Short Stature in Early Childhood.

作者信息

Davallow Ghajar Ladan, DeBoer Mark Daniel

机构信息

Virginia Commonwealth University, Richmond, VA, USA.

University of Virginia, Charlottesville, VA, USA.

出版信息

Clin Pediatr (Phila). 2020 May;59(4-5):401-410. doi: 10.1177/0009922820902437. Epub 2020 Feb 1.

Abstract

Our objective was to evaluate the risk of short stature in children with attention-deficit/hyperactivity disorder (ADHD) and the effect of ADHD and its treatment on height-for-age score (HAZ) and body mass index-for-age score (BMIZ) in early childhood. We evaluated 7603 children from the Early Childhood Longitudinal Study-Kindergarten Cohort 2011 and found that children with ADHD had lower HAZ at second and fourth grades and lower BMIZ at K to fourth grade. Children with ADHD at fourth grade had almost 4 times higher odds of short stature. Children with ADHD at K grew at a slower rate from K to fourth grade (difference in ΔHAZ = 0.23, 95% confidence interval = 0.04-0.42) and had less gain in BMI (difference in ΔBMIZ = 0.16, 95% confidence interval = 0.03-0.29). Longer duration of ADHD medication use was associated with lower HAZ at fourth grade and slower growth from K to fourth grade. These data may assist pediatricians in considering risk of poor growth in children with ADHD.

摘要

我们的目标是评估注意力缺陷多动障碍(ADHD)患儿身材矮小的风险,以及ADHD及其治疗对幼儿期年龄别身高评分(HAZ)和年龄别体重指数评分(BMIZ)的影响。我们对来自2011年幼儿纵向研究 - 幼儿园队列的7603名儿童进行了评估,发现患有ADHD的儿童在二年级和四年级时HAZ较低,在幼儿园至四年级时BMIZ较低。四年级患有ADHD的儿童身材矮小的几率几乎高出4倍。幼儿园时患有ADHD的儿童从幼儿园到四年级的生长速度较慢(ΔHAZ差异 = 0.23,95%置信区间 = 0.04 - 0.42),BMI增加较少(ΔBMIZ差异 = 0.16,95%置信区间 = 0.03 - 0.29)。ADHD药物使用时间较长与四年级时较低的HAZ以及从幼儿园到四年级较慢的生长速度相关。这些数据可能有助于儿科医生考虑ADHD患儿生长发育不良的风险。

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