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从英国视角看药物医学实践中伦理原则的演变

Evolution of Ethical Principles in the Practice of Pharmaceutical Medicine From a UK Perspective.

作者信息

Morris Thomas, Brostoff Joshua M, Stonier Peter David, Boyd Alan

机构信息

Faculty of Pharmaceutical Medicine, Royal College of Physicians, London, United Kingdom.

出版信息

Front Pharmacol. 2020 Jan 15;10:1525. doi: 10.3389/fphar.2019.01525. eCollection 2019.

Abstract

Pharmaceutical medicine has evolved to be a distinct medical scientific discipline over time. Pharmaceutical medicine has distinctive features related to complex innovative medicines development activities in an often commercially focused competitive environment. This sometimes uneasy mix of professionalism and commercialisation demands of its medical and scientific researchers alike, a focus on strict adherence to ethical standards, guidelines, practices and behaviors in the interest of delivering new, effective, high-quality lifesaving and life-enhancing medicines quickly and reliably to patients in need. To support the speciality, codes of ethical standards and practices have been developed, with several being recently updated. These various codes are outlined in this paper along with relevant historical perspectives and interrelationship with concepts of professionalism. Reflecting the longer history of pharmaceutical medicine as a speciality in the UK and experience of the authors, there is a focus on the UK for the historical perspectives.

摘要

随着时间的推移,药物医学已发展成为一门独特的医学科学学科。在通常以商业为重点的竞争环境中,药物医学具有与复杂创新药物研发活动相关的独特特征。这种专业精神与商业化的有时不太协调的结合,对其医学和科研人员都提出了要求,即要专注于严格遵守道德标准、准则、实践和行为,以便迅速而可靠地为有需要的患者提供新的、有效的、高质量的救命和改善生活的药物。为了支持这一专业领域,已制定了道德标准和实践准则,其中一些最近进行了更新。本文概述了这些不同的准则以及相关的历史观点,以及它们与专业精神概念的相互关系。鉴于药物医学在英国作为一门专业的历史较长以及作者的经验,历史观点部分将重点关注英国。

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