Rudrapatna Vivek A, Butte Atul J
Bakar Computational Health Sciences Institute.
Division of Gastroenterology, Department of Medicine, and.
J Clin Invest. 2020 Feb 3;130(2):565-574. doi: 10.1172/JCI129197.
Real-world data (RWD) continue to emerge as a new source of clinical evidence. Although the best-known use case of RWD has been in drug regulation, RWD are being generated and used by many other parties, including biopharmaceutical companies, payors, clinical researchers, providers, and patients. In this Review, we describe 21 potential uses for RWD across the spectrum of health care. We also discuss important challenges and limitations relevant to the translation of these data into evidence.
真实世界数据（RWD）正不断成为临床证据的新来源。尽管RWD最为人熟知的应用案例是在药物监管方面，但包括生物制药公司、支付方、临床研究人员、医疗服务提供者和患者在内的许多其他方也在生成和使用RWD。在本综述中，我们描述了RWD在整个医疗保健领域的21种潜在用途。我们还讨论了将这些数据转化为证据所涉及的重要挑战和局限性。
