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评估2种超声指标作为预测孕妇喉镜检查困难的指标:一项前瞻性双盲研究。

Evaluation of 2 ultrasonic indicators as predictors of difficult laryngoscopy in pregnant women: A prospective, double blinded study.

作者信息

Xu Lili, Dai Shaobing, Sun Lihong, Shen Jianjun, Lv Changcheng, Chen Xinzhong

机构信息

Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province.

Department of Anesthesia, The Second Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang Province, China.

出版信息

Medicine (Baltimore). 2020 Jan;99(3):e18305. doi: 10.1097/MD.0000000000018305.

Abstract

BACKGROUND

Ultrasonic measurements of tongue thickness and condylar translation were recently introduced to predict difficult laryngoscopy in non-obstetric patients. We designed the present study to evaluate the performance of these two ultrasonic indicators in predicting difficult laryngoscopy in healthy parturients.

METHODS

The 119 parturients undergoing elective cesarean delivery were enrolled. Tongue thickness and condylar translation measured by ultrasonography, and Modified Mallampati test (MMT) score, inter-incisor distance (IID) and modified Cormack-Lehane grading system (MCLS) were measured and recorded before anesthesia. The primary outcome was difficult laryngoscopy defined as MCLS 3 or 4. The association between these variables and difficult laryngoscopy were analyzed by using multivariable logistic regression and receiver operating characteristic (ROC) curve.

RESULTS

Compared to the Easy Laryngoscopy Group, the tongue thickness was significantly higher and the condylar translation and IID were significantly lower in the Difficult Laryngoscopy Group. Tongue thickness and condylar translation but not MMT score and IID were proved to be two independent predictors for difficult laryngoscopy by multivariate logistic regression, with the odds ratios of 2.554 (95% confidence interval (CI), 1.715 to 3.802) and 0.457 (95% CI, 0.304 to 0.686). The area under the ROC curve to predict difficult laryngoscopy for tongue thickness was 0.93 (95% CI, 0.88-0.98) and for condylar translation was 0.77 (95% CI, 0.67-0.86), which were significantly higher than those for MMT score (0.67, 95% CI, 0.56-0.77) and IID (0.65, 95% CI, 0.55-0.76).

CONCLUSIONS

Compared with MMT and IID, tongue thickness and condylar translation measured by ultrasonography appear to be better indicators for predicting difficult laryngoscopy in parturients.The trial was registered at the Chinese Clinical Trial Registry (ChiCTR)(www.chictr.org), registration number ChiCTR-ICR-1800019991.

摘要

背景

最近引入了超声测量舌厚度和髁突移位来预测非产科患者的困难喉镜检查。我们设计了本研究以评估这两个超声指标在预测健康产妇困难喉镜检查中的性能。

方法

纳入119例行择期剖宫产的产妇。在麻醉前通过超声测量舌厚度和髁突移位,并测量和记录改良Mallampati试验(MMT)评分、门齿间距离(IID)和改良Cormack-Lehane分级系统(MCLS)。主要结局是定义为MCLS 3或4的困难喉镜检查。使用多变量逻辑回归和受试者工作特征(ROC)曲线分析这些变量与困难喉镜检查之间的关联。

结果

与容易喉镜检查组相比,困难喉镜检查组的舌厚度明显更高,髁突移位和IID明显更低。多变量逻辑回归证明,舌厚度和髁突移位而非MMT评分和IID是困难喉镜检查的两个独立预测因素,优势比分别为2.554(95%置信区间(CI),1.715至3.802)和0.457(95%CI,0.304至0.686)。预测困难喉镜检查的舌厚度的ROC曲线下面积为0.93(95%CI,0.88 - 0.98),髁突移位的为0.77(95%CI,0.67 - 0.86),均显著高于MMT评分(0.67,95%CI,0.56 - 0.77)和IID(0.65,95%CI,0.55 - 0.76)。

结论

与MMT和IID相比,超声测量的舌厚度和髁突移位似乎是预测产妇困难喉镜检查的更好指标。该试验在中国临床试验注册中心(ChiCTR)(www.chictr.org)注册,注册号为ChiCTR - ICR - 1800019991。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08ee/7220303/afc0a5021b1f/medi-99-e18305-g001.jpg

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