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早期二次宫腔镜检查联合宫腔球囊扩张对宫腔粘连患者生殖结局的影响。

Effects of early second-look hysteroscopy combined with intrauterine balloon dilatation on reproductive outcomes for women with intrauterine adhesions.

机构信息

Department of Gynecology, Shenyang Women's and Children's Hospital, Shenyang, China.

Reproductive Center, Shenyang Women's and Children's Hospital, Shenyang, China.

出版信息

Int J Gynaecol Obstet. 2020 May;149(2):192-196. doi: 10.1002/ijgo.13108. Epub 2020 Feb 21.

Abstract

OBJECTIVE

To investigate the effect of early second-look office hysteroscopy combined with intrauterine balloon dilatation on prognosis and pregnancy rate for women with intrauterine adhesions.

METHODS

A retrospective analysis of 156 women diagnosed with intrauterine adhesions by hysteroscopy at Shenyang Women's and Children's Hospital, China, from April 2017 to January 2019. The study women underwent intrauterine balloon dilatation 10 days after transcervical resection of adhesion (TCRA) and hysteroscopy 20 days after TCRA (n=81). The control women underwent hysteroscopy 3 months after TCRA (n=75). Estrogen and aspirin were routinely administered postoperatively to all women. Data, including American Fertility Society (AFS) scores assessed by hysteroscopy, endometrial thickness measured by ultrasound, and menstruation and pregnancy outcomes assessed by interview, were compared between the two groups.

RESULTS

The degree of intrauterine adhesions, menstrual status, and endometrial thickness were improved in both groups after TCRA. Greater improvement in AFS score, menstruation, and endometrial thickness was observed in the study group than in the control group. After follow-up, more women in the study group achieved pregnancy (48.1% vs 30.7%, P<0.05).

CONCLUSION

Early second-look of hysteroscopy combined with intrauterine balloon dilatation after hysteroscopic TRCA might improve the prognosis and postoperative pregnancy rate for women with intrauterine adhesions.

摘要

目的

探讨宫腔镜下宫腔粘连分解术后早期行二次宫腔镜检查联合宫内球囊扩张对宫腔粘连患者预后及妊娠率的影响。

方法

回顾性分析 2017 年 4 月至 2019 年 1 月于中国沈阳市妇婴医院因宫腔镜检查诊断为宫腔粘连的 156 例患者的临床资料。术后 10 d 行宫腔球囊扩张,20 d 行宫腔镜检查(研究组,n=81);术后 3 个月行宫腔镜检查(对照组,n=75)。所有患者术后常规给予雌激素和阿司匹林治疗。比较两组患者宫腔镜下宫腔粘连评分、超声测量子宫内膜厚度、月经及妊娠结局。

结果

两组患者宫腔粘连程度、月经状态和子宫内膜厚度均在 TCRA 后得到改善。研究组 AFS 评分、月经及子宫内膜厚度的改善程度明显优于对照组。随访后,研究组妊娠率(48.1%)高于对照组(30.7%)(P<0.05)。

结论

宫腔粘连分解术后宫腔镜下早期二次检查联合宫内球囊扩张可改善宫腔粘连患者的预后和术后妊娠率。

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