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革新弥漫性子宫平滑肌瘤病的治疗:一例关于使用胸腔组织钳进行“无膨胀”宫腔镜子宫肌瘤切除术的病例报告及文献综述

Revolutionizing diffuse uterine leiomyomatosis treatment: A case report and literature review on "no-distension" hysteroscopic myomectomy with thoracic tissue forceps.

作者信息

Zhang Zhengping, Yang Haikun, Pan Ru

机构信息

Department of Gynecology Oncologic Center, Meizhou People's Hospital, Meizhou, China.

出版信息

Int J Gynaecol Obstet. 2025 Jan;168(1):87-93. doi: 10.1002/ijgo.15800. Epub 2024 Jul 28.

Abstract

Diffuse uterine leiomyomatosis (DUL) is a prevalent leiomyoma variant in women of childbearing age, characterized by a uniformly enlarged uterus with numerous interconnected small myomas. Given that most DUL patients are in their reproductive years, treatments that preserve fertility are increasingly vital. This case report introduces an innovative hysteroscopic technique that forgoes uterine distension to remove multiple submucosal fibroids in a single procedure, maintaining endometrial integrity and fertility. A 27-year-old single woman experienced prolonged and heavier menstruation. Magnetic resonance imaging (MRI) scans showed an enlarged uterus with several round-like masses in the uterine wall/submucosa. Addressing the patient's financial limitations and treatment preferences, a groundbreaking hysteroscopic surgery was performed using thoracic tissue forceps, alongside bedside ultrasonography, enabling fibroid excision without uterine distension. In total, 38 uterine fibroids were successfully excised without complications such as uterine perforation or hyponatremia. According to the FIGO classification system: three were type III, nine were type II, 15 were type I, and 11 were type 0. Postoperative follow-up indicated normalized menstrual cycles, improved hemoglobin levels, and no recurrence of fibroids. A hysteroscopic examination 1 month after surgery revealed no significant fibroids or endometrial thickening. This case report underscores the effectiveness of a novel hysteroscopic surgical approach in treating DUL. This method eliminates the need for multiple staged surgeries and the risks of endometrial damage inherent in traditional techniques. It offers a minimally invasive, fertility-preserving alternative for young DUL patients, marking a significant advancement in gynecologic surgery.

摘要

弥漫性子宫平滑肌瘤病(DUL)是育龄期女性中一种常见的平滑肌瘤变体,其特征是子宫均匀增大,伴有众多相互连接的小肌瘤。鉴于大多数DUL患者处于生育年龄,保留生育能力的治疗方法变得越来越重要。本病例报告介绍了一种创新的宫腔镜技术,该技术无需子宫扩张即可在单次手术中切除多个黏膜下肌瘤,同时保持子宫内膜的完整性和生育能力。一名27岁的单身女性经历了经期延长和经量增多。磁共振成像(MRI)扫描显示子宫增大,子宫壁/黏膜下有几个圆形肿块。考虑到患者的经济限制和治疗偏好,使用胸腔组织钳并结合床边超声进行了开创性的宫腔镜手术,实现了无需子宫扩张的肌瘤切除。总共成功切除了38个子宫肌瘤,未出现子宫穿孔或低钠血症等并发症。根据国际妇产科联盟(FIGO)分类系统:III型3个,II型9个,I型15个,0型11个。术后随访表明月经周期恢复正常,血红蛋白水平提高,肌瘤无复发。术后1个月的宫腔镜检查显示无明显肌瘤或子宫内膜增厚。本病例报告强调了一种新型宫腔镜手术方法治疗DUL的有效性。该方法无需多次分期手术,消除了传统技术中固有的子宫内膜损伤风险。它为年轻的DUL患者提供了一种微创、保留生育能力的替代方案,标志着妇科手术的重大进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7006/11649851/d88f24c09ae7/IJGO-168-87-g004.jpg

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