Department of Family Planning, Women and Children's Hospital, School of Medicine, Xiamen University, Siming District, Zhenhai Road, Xiamen, 361005, Fujian, China.
Department of Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China.
Arch Gynecol Obstet. 2023 Jun;307(6):1873-1882. doi: 10.1007/s00404-023-06993-y. Epub 2023 Mar 10.
This study aimed to compare the efficacy of a special kind of intrauterine balloon (IUB) and that of an intrauterine contraception device (IUD) for patients with intrauterine adhesions (IUAs) after transcervical resection of adhesion (TCRA).
In this retrospective cohort study, after TCRA, 31 patients received a special IUB, and 38 patients received an IUD. The Fisher exact test, logistic regression method, Kaplan-Meier method and Cox proportional hazards regression model were used for statistical analysis. A two-sided value of P < 0.05 was considered statistically significant.
The readhesion rate significantly differed between the IUB group and IUD group, at 15.39% and 54.06%, respectively (P = 0.002). For recurrent moderate IUA, patients in the IUB group had lower scores than patients in the IUD group (P = 0.035). There was a significant difference in the intrauterine pregnancy rate of IUA patients in the IUB group and IUD group after treatment, with rates of 55.56% and 14.29%, respectively (P = 0.015).
Patients in the special IUB group had better outcomes than those in the IUD group, which has a certain guiding significance for clinical work.
本研究旨在比较宫腔粘连(IUAs)经宫颈粘连切除术(TCRA)后,特殊宫腔内球囊(IUB)与宫内节育器(IUD)的疗效。
本回顾性队列研究中,31 例患者在 TCRA 后接受特殊 IUB,38 例患者接受 IUD。采用 Fisher 确切检验、logistic 回归法、Kaplan-Meier 法和 Cox 比例风险回归模型进行统计学分析。双侧 P 值<0.05 为统计学显著差异。
IUB 组和 IUD 组的再粘连率分别为 15.39%和 54.06%,差异有统计学意义(P=0.002)。对于复发性中度 IUA,IUB 组患者的评分低于 IUD 组(P=0.035)。治疗后 IUA 患者的宫内妊娠率在 IUB 组和 IUD 组之间存在显著差异,分别为 55.56%和 14.29%(P=0.015)。
特殊 IUB 组患者的结局优于 IUD 组,对临床工作具有一定的指导意义。