Department of Hypertension, Henan University People's Hospital, Zhengzhou, Henan, China.
Department of Hypertension, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Clin Exp Hypertens. 2020 May 18;42(4):376-380. doi: 10.1080/10641963.2020.1723617. Epub 2020 Feb 4.
Obesity, dyslipidemia and diabetes have been recognized as risk factors of hypertension in the general population. This study focused on college students and correlations between serum lipids, serum uric acid, fasting plasma glucose, serum creatinine, body mass index, brachial-ankle pulse wave velocity and hypertension. The results suggested that there was no relevance between serum lipids and hypertension. However, it came out that hypertension is associated with normal fasting plasma glucose, BMI (thinness and normal weight), normal serum creatinine. A total of 5185 students were enrolled, and their blood pressure, height and weight were measured. 285 of the students were selected to take physical examinations including serum uric acid, total cholesterol, low-density lipoprotein cholesterol, triglyceride, high-density lipoprotein cholesterol, fasting plasma glucose, serum creatinine, blood urea nitrogen, ankle-brachial index and brachial-ankle pulse wave velocity measured. The values of systolic blood pressure(SBP), diastolic blood pressure(DBP), serum uric acid, fasting plasma glucose(FPG), serum creatinine, body mass index(BMI), and brachial-ankle pulse wave velocity(baPWV) were higher in hypertension group than those in non-hypertension group ). Logistic regression showed correlations between hypertension and hyperuricemia (), obesity (), fasting plasma glucose () and brachial-ankle pulse wave velocity (). The was . We can draw a conclusion that hyperuricemia, obesity, fasting plasma glucose and brachial-ankle pulse wave velocity, listed in descending order of influence, are risk factors for hypertension in college students.
肥胖、血脂异常和糖尿病已被公认为一般人群高血压的危险因素。本研究关注的是大学生，以及血清脂质、血清尿酸、空腹血糖、血清肌酐、体重指数、肱踝脉搏波速度与高血压之间的相关性。结果表明，血清脂质与高血压之间没有相关性。然而，高血压与正常空腹血糖、BMI（消瘦和正常体重）、正常血清肌酐有关。共纳入 5185 名学生，测量其血压、身高和体重。选择 285 名学生进行体检，包括血清尿酸、总胆固醇、低密度脂蛋白胆固醇、甘油三酯、高密度脂蛋白胆固醇、空腹血糖、血清肌酐、血尿素氮、踝臂指数和肱踝脉搏波速度。高血压组的收缩压（SBP）、舒张压（DBP）、血清尿酸、空腹血糖（FPG）、血清肌酐、体重指数（BMI）和肱踝脉搏波速度（baPWV）值均高于非高血压组。Logistic 回归显示高血压与高尿酸血症（）、肥胖（）、空腹血糖（）和肱踝脉搏波速度（）相关。 的值为。我们可以得出结论，高尿酸血症、肥胖、空腹血糖和肱踝脉搏波速度按影响程度降序排列，是大学生高血压的危险因素。
