Medicines Management & Pharmacy Services, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Cardiology Department, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
BMC Cardiovasc Disord. 2020 Feb 3;20(1):46. doi: 10.1186/s12872-020-01362-y.
The 'My Experience of Taking Medicines' (MYMEDS) questionnaire is a self-reporting tool for identifying modifiable adherence barriers among individuals prescribed post-myocardial infarction (MI) secondary prevention medicines (SPM) in clinical practice. It was found to be a useful tool to support the conduction of patient-centred consultation in cardiology outpatient leading to improved outcomes including better adherence to SPM and patient satisfaction. This study describes the rationale and development of the MYMEDS tool, its performance and usefulness in identifying modifiable barriers to adherence in cardiology medical practice including user feedback of 204 consecutive post-MI patients who completed an evaluation based on MYMEDS.
Modifiable non-adherence factors were initially identified based on literature review and stakeholder feedback. A draft MYMEDS questionnaire was piloted in 10 patients and adapted accordingly. The final version comprises six sections, covering current medicines, understanding and satisfaction with medicines, concerns about medicines, practical adherence barriers, fitting medicines into daily routine, and adherence to individual SPMs. The questionnaire was mailed to post-MI patients who then attended an outpatient medicines optimisation clinic.
Mean age was 70.5 years and 67.6% were male. The tool was effective in revealing modifiable adherence barriers that could be addressed during the consultation. There were high rates of concern that SPMs could be harmful (33.2%) or overprescribed (43.2%), practical issues with swallowing medicines (8.2%), opening packaging (7.3%) or accessing repeat prescriptions (5.2%), forgetfulness (19.7%), and concerns about inconvenience (13.5%). Mean number of barriers per patient was 1.8 ± 1.5. The medications most commonly associated with non-adherence were statins (21.5%), angiotensin II receptor blockers (21.1%), and antiplatelet agents (18.5%). In total, 42.5% of patients acknowledged non-adherence behaviour. Patient feedback on MYMEDS was positive, with near-unanimous agreement that it was simple, clear and not too long, and that it enabled them to raise any concerns they had about their medicines. Patients reported that their individual medicines related needs were better addressed.
MYMEDS is a practical tool that can successfully identify modifiable barriers to SPM adherence which can be addressed in a clinical setting. It can be easily rolled out in daily clinical practice to enable individualised person-centred medicines optimisation consultation.
“用药体验”(MYMEDS)问卷是一种自我报告工具,用于识别临床实践中开具心梗二级预防药物(SPM)后患者的可改变用药依从性障碍。它是一种有用的工具,可支持心内科门诊开展以患者为中心的咨询,从而改善结局,包括更好地依从 SPM 和提高患者满意度。本研究介绍了 MYMEDS 工具的原理和开发过程,及其在识别心内科医疗实践中可改变的用药依从性障碍方面的表现和实用性,包括对 204 例心梗后患者的反馈,这些患者根据 MYMEDS 进行了评估。
最初基于文献回顾和利益相关者的反馈确定了可改变的不依从因素。对 MYMEDS 问卷草案进行了 10 例患者的预试验,并进行了相应的调整。最终版本包括六个部分,涵盖当前药物、对药物的理解和满意度、对药物的担忧、实际用药障碍、将药物纳入日常生活、以及对个别 SPM 的依从性。问卷寄给心梗后患者,然后他们到门诊药物优化诊所就诊。
平均年龄为 70.5 岁,67.6%为男性。该工具能有效地揭示可在咨询中解决的可改变的用药依从性障碍。患者普遍担心 SPM 可能有害(33.2%)或过度处方(43.2%)、吞咽药物(8.2%)、打开包装(7.3%)或获取重复处方(5.2%)、健忘(19.7%)和担心不便(13.5%)等实际问题。每位患者的障碍平均数量为 1.8±1.5。最常与不依从相关的药物是他汀类药物(21.5%)、血管紧张素Ⅱ受体阻滞剂(21.1%)和抗血小板药物(18.5%)。共有 42.5%的患者承认存在不依从行为。患者对 MYMEDS 的反馈是积极的,几乎一致认为它简单、清晰、不太长,并使他们能够提出任何与药物相关的担忧。患者报告说,他们的个人药物相关需求得到了更好的满足。
MYMEDS 是一种实用的工具,能够成功识别 SPM 依从性的可改变障碍,并可在临床环境中加以解决。它可以很容易地在日常临床实践中推广,以实现个体化的以患者为中心的药物优化咨询。