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与部分脾栓塞术治疗脾功能亢进相关的不良事件:一项系统评价

Adverse Events Related to Partial Splenic Embolization for the Treatment of Hypersplenism: A Systematic Review.

作者信息

Talwar Abhinav, Gabr Ahmed, Riaz Ahsun, Desai Kush, Thornburg Bartley, Mouli Samdeep, Lewandowski Robert J, Salem Riad

机构信息

Department of Radiology, Section of Interventional Radiology, Northwestern University, Chicago, Illinois.

Department of Radiology, Section of Interventional Radiology, Northwestern University, Chicago, Illinois; Department of Medicine, Division of Hematology and Oncology, Northwestern University, Chicago, Illinois.

出版信息

J Vasc Interv Radiol. 2020 Jul;31(7):1118-1131.e6. doi: 10.1016/j.jvir.2019.08.015. Epub 2020 Feb 1.

Abstract

Partial splenic embolization is a common procedure that reduces thrombocytopenia in patients with hypersplenism. The present review evaluated the adverse event profile of partial splenic embolization detailed in 30 articles. Although the technical success rate of the procedure in these papers is high, many patients experienced postprocedural complications. Minor complications such as postembolization syndrome occurred frequently. Major complications were less frequent but sometimes resulted in mortality. Underlying liver dysfunction and high infarction rates may be risk factors leading to major complications. Interventional radiologists should be aware of the complication profile of this procedure and further advance research in techniques dealing with hypersplenism.

摘要

部分脾栓塞术是一种常见的可减轻脾功能亢进患者血小板减少症的手术。本综述评估了30篇文章中详述的部分脾栓塞术的不良事件情况。尽管这些论文中该手术的技术成功率很高,但许多患者术后出现了并发症。诸如栓塞后综合征等轻微并发症频繁发生。严重并发症虽较不常见,但有时会导致死亡。潜在的肝功能障碍和高梗死率可能是导致严重并发症的危险因素。介入放射科医生应了解该手术的并发症情况,并进一步推进针对脾功能亢进治疗技术的研究。

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