Kormano M, Kock B, Brotherus V, Lindfors O, Lindstrom B
Invest Radiol. 1977 Jan-Feb;12(1):74-80. doi: 10.1097/00004424-197701000-00015.
A microangiographic study of 17 rejected and surgically removed human kidney transplants, three transplants removed for other reasons and two adequately perfused and preserved but not transplanted cadaver kidneys was performed. Transplants rejected with acute clinical course showed poor or variable glomerular filling and tapering cortical arteries with no impairment of medullary perfusion, more extensively in those transplants showing poor initial function. Chronic rejection, independent of other parameters showed lack of cortical perfusion, and glomerular filling; impaired perfusion of whole segments, arterial wall narrowing and changes secondary to kidney shrinkage. The radiographic patterns of chronic and acute rejection were distinguishable from each other and from nonrejected specimens.
对17例被排斥并经手术切除的人肾移植、3例因其他原因切除的移植肾以及2例灌注良好、保存完好但未移植的尸体肾进行了微血管造影研究。临床病程为急性排斥的移植肾显示肾小球充盈不良或变化不定，皮质动脉逐渐变细，而髓质灌注无损害，在那些初始功能较差的移植肾中更为广泛。慢性排斥反应，与其他参数无关，表现为皮质灌注缺乏、肾小球充盈不良；整个节段灌注受损、动脉壁狭窄以及肾萎缩继发的变化。慢性和急性排斥反应的影像学表现彼此之间以及与未被排斥的标本都可区分。
