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消防员服装的封闭效应导致皮肤屏障受损。

Skin Barrier Impairment due to the Occlusive Effect of Firefighter Clothing.

机构信息

Radboud University Nijmegen Medical Centre, Department of Dermatology, GL Nijmegen, The Netherlands.

Institute for Safety, Knowledge Center Occupational Safety, RP Zoetermeer, The Netherlands.

出版信息

Ann Work Expo Health. 2020 Mar 10;64(3):331-337. doi: 10.1093/annweh/wxaa005.

DOI:10.1093/annweh/wxaa005
PMID:32016377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7571499/
Abstract

At fire scenes, firefighters are exposed to potentially harmful substances. Besides inhalation of these products, also skin contamination and the risk of dermal absorption is getting more attention. In this perspective, skin barrier impairment due to the occlusive effect of firefighter clothes could enhance the risk of penetration of hazardous substances. The effect of a firefighter jacket and cellophane on the skin was studied in a paired comparison involving 16 volunteers. Biophysical parameters were measured before, immediately after and 30 min after ending the occlusion. Reflectance confocal microscopy was used to study the skin morphology. Immediately after wearing a firefighter jacket, Transepidermal Water Loss values were significantly increased. This is an indication of an occlusive effect of the firefighter jacket. The skin barrier was fully restored after 30 min after occlusion with cellophane or wearing a firefighter jacket.

摘要

在火灾现场,消防员会接触到潜在有害的物质。除了吸入这些产品外,皮肤污染和皮肤吸收的风险也越来越受到关注。从这个角度来看,由于消防服的密闭作用而导致的皮肤屏障受损,可能会增加有害物质渗透的风险。本研究通过 16 名志愿者的配对比较,研究了消防服上衣和玻璃纸对皮肤的影响。在开始密闭之前、密闭结束后即刻和 30 分钟后,测量了生物物理参数。使用反射共聚焦显微镜研究皮肤形态。穿消防服上衣后,立即观察到经皮水分流失值显著增加,这表明消防服上衣具有密闭作用。玻璃纸或穿消防服上衣 30 分钟后,皮肤屏障完全恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16ce/7571499/2e8a7a2a4ff7/wxaa005_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16ce/7571499/2e8a7a2a4ff7/wxaa005_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16ce/7571499/2e8a7a2a4ff7/wxaa005_fig1.jpg

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本文引用的文献

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