Schupp J C, Prasse A, Erythropel H C
Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
Klinik für Pneumologie, Medizinische Hochschule Hannover, und Fraunhofer ITEM, DZL BREATH, Hannover, Deutschland.
Pneumologie. 2020 Feb;74(2):77-87. doi: 10.1055/a-1078-8126. Epub 2020 Feb 3.
Beginning in April of 2019, the US saw > 2,000 cases of hospitalized, often young, patients with severe acute lung injury, of which over 40 died, and the only existing connection between patients was their use of electronic cigarettes (e-cigarettes). The acronym EVALI ("") has since been established for the condition. This review article is intended to provide an overview of recent, mainly US literature on EVALI, including the case definition, epidemiology, clinical presentation, typical disease progression, as well as potential triggers. Ancillary to this, the review further provides a general overview of the basic function of e-cigarettes, the ingredients of the liquids used in these (e-liquids), as well as a brief description of the associated potential inhalation risks.
从2019年4月开始，美国出现了2000多例住院的严重急性肺损伤患者，这些患者往往较为年轻，其中40多人死亡，而这些患者之间唯一的联系是他们都使用电子烟。此后，“电子烟或雾化产品使用相关肺损伤”（EVALI）这一术语被用来指代这种病症。这篇综述文章旨在概述近期主要来自美国的关于EVALI的文献，包括病例定义、流行病学、临床表现、典型疾病进展以及潜在触发因素。在此基础上，该综述还进一步概述了电子烟的基本功能、电子烟使用的液体（电子烟液）成分，以及对相关潜在吸入风险的简要描述。
