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使用事件相关电位评估精神分裂症患者的认知缺陷以及使用脑电图生物反馈评估康复影响,这些患者均被诊断为精神分裂症。

Evaluation of cognitive deficits in schizophrenia using event-related potentials and rehabilitation influences using EEG Biofeedback in patients diagnosed with schizophrenia.

作者信息

Markiewcz Renata, Masiak Jolanta

机构信息

Uniwersytet Medyczny w Lublinie, Zakład Pielęgniarstwa Psychiatrycznego.

Uniwersytet Medyczny w Lublinie, Katedra Psychiatrii, Samodzielna Pracownia Badań Neurofizjologicznych.

出版信息

Psychiatr Pol. 2019 Dec 31;53(6):1261-1273. doi: 10.12740/PP/OnlineFirst/102622.

DOI:10.12740/PP/OnlineFirst/102622
PMID:32017816
Abstract

Cognitive deficits in schizophrenic patients have a chronic and negative effect on patients' social functioning. Antipsychotic drugs do not sufficiently improve cognitive functions. In this study, an analysis of previous studies on cognitive functions using event-related potentials in schizophrenia patients was conducted on the basis of available publications (Pubmed, Scopus). The studies indicate numerous deviations at various stages of information processing in patients diagnosed with schizophrenia when compared to healthy subjects, and this justifies the need for the development of new methods influencing the bioelectric brain activity in cognitive rehabilitation of these patients. EEG Biofeedback is a method which could be used for rehabilitation of cognitive functions in schizophrenia patients. Despite it being used in practice, the importance of EEG Biofeedback as a rehabilitation influence on cognitive functions in schizophrenia has not been fully ascertained. This paper analyses the results of previous studies on the effect of EEG Biofeedback therapy on cognitive functions as a possible method to be used in the rehabilitation of schizophrenia patients. Currently, the body of research that may prove the value of this method in the rehabilitation of patients with schizophrenia appears to be insufficient, and there is no scientific evidence from randomized studies for the usefulness of EEG Biofeedback in schizophrenia treatment. At the moment, the recommendation of this method in the cognitive rehabilitation of patients is a therapeutic experiment. The researchers, on the basis of an analysis of clinical cases, currently propose that EEG Biofeedback is conducted in patients diagnosed with schizophrenia by experienced practitioners, paying particular attention to strengthening alpha in the right parietal region.

摘要

精神分裂症患者的认知缺陷对其社会功能产生长期负面影响。抗精神病药物不能充分改善认知功能。在本研究中,基于现有出版物(PubMed、Scopus)对先前关于精神分裂症患者认知功能的事件相关电位研究进行了分析。研究表明,与健康受试者相比,被诊断为精神分裂症的患者在信息处理的各个阶段存在诸多偏差,这证明有必要开发新方法来影响这些患者认知康复中的脑生物电活动。脑电图生物反馈是一种可用于精神分裂症患者认知功能康复的方法。尽管它已在实践中使用,但脑电图生物反馈作为对精神分裂症认知功能的康复影响的重要性尚未完全确定。本文分析了先前关于脑电图生物反馈疗法对认知功能影响的研究结果,作为一种可能用于精神分裂症患者康复的方法。目前,可能证明该方法对精神分裂症患者康复有价值的研究似乎不足,并且没有来自随机研究的科学证据证明脑电图生物反馈在精神分裂症治疗中的有效性。目前,在患者认知康复中推荐这种方法是一种治疗实验。研究人员在对临床病例分析的基础上,目前建议由经验丰富的从业者对被诊断为精神分裂症的患者进行脑电图生物反馈,尤其要注意增强右顶叶区域的阿尔法波。

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