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[颞动脉炎——诊断与治疗控制]

[Temporal arteritis--diagnosis and therapeutic control].

作者信息

Ulrich C, Ulrich D, Kornotzki M, Ulrich W D

机构信息

Klinik für Augenkrankheiten, Karl-Marx-Universität Leipzig.

出版信息

Z Gesamte Inn Med. 1988 Sep 15;43(18):526-30.

PMID:3201806
Abstract

33 patients suffering from temporal arteriitis (Morbus Horton) were investigated noninvasively by Oculo-Oscillo-Dynamography (OODG), Orbita-Dynamography (ODG) and Temporalis-Dynamography (TDG). The ocular, orbital and temporal oscillograms and oscillodynamograms revealed characteristic and unmistakable alterations; i.e., striking reduction of the pulse volumes and a decrease of the blood pressures in the respective circulatory regions as a result of a stenosing and occluding vascular process. The 3 methods yielded typical patterns of the occluding process, which led to the conclusion that in untreated persons the stenosing process of the arteritis cranialis tends to start in the vascular branches of the external carotid artery and subsequently includes branches of the internal carotid system, such as the ophthalmic artery. High doses of prednisolone resulted in reopening of the vessels that had been stenosed and occluded by arteritis, and in most cases restored normal circulation in the regions examined within several weeks or months. From the investigations made on 66 eyes of the 33 patients, the authors conclude that combined use of OODG, ODG, and TDG makes it possible to diagnose temporal arteritis with a high degree of certainty. In all 33 cases the disease was diagnosed with OODG, ODG and TDG and confirmed histologically. Since the OODG, ODG, TDG examinations are well tolerated by the patient and can be repeated at any time, it is suggested to employ them for the supervision of therapy as well to detect any possible relapse of the inflammatory occluding vascular process.

摘要

对33例颞动脉炎( Horton病)患者采用眼动振荡血流动力学(OODG)、眶动血流动力学(ODG)和颞肌动血流动力学(TDG)进行了无创检查。眼、眶和颞部的振荡图和振荡血流图显示出特征性且明确无误的改变,即由于血管狭窄和闭塞过程,相应循环区域的脉搏容积显著降低,血压下降。这三种方法产生了闭塞过程的典型模式,由此得出结论:在未经治疗的患者中,颅动脉炎的狭窄过程往往始于颈外动脉的血管分支,随后累及颈内动脉系统的分支,如眼动脉。大剂量泼尼松龙可使因动脉炎而狭窄和闭塞的血管重新开放,在大多数情况下,在数周或数月内可使所检查区域的循环恢复正常。通过对33例患者的66只眼睛进行的检查,作者得出结论,联合使用OODG、ODG和TDG能够高度准确地诊断颞动脉炎。在所有33例病例中,通过OODG、ODG和TDG诊断出该疾病,并经组织学证实。由于OODG、ODG、TDG检查患者耐受性良好且可随时重复进行,建议将其用于治疗监测,以及检测炎症性闭塞血管过程的任何可能复发情况。

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