Paar G H, Bezzenberger U, Lorenz-Meyer H
Klinik für Psychotherapie und Psychosomatik Essen.
Z Gastroenterol. 1988 Oct;26(10):648-57.
The following study examines the correlation of psychosocial stress and disease activity in patients suffering from chronic inflammatory bowel diseases. 70 patients with Crohn's disease and 44 patients with ulcerative colitis took part in this study. Using an inventory for the registration of life-changing events, psychosocial life-events of the last 24 months were inquired. The disease activity was registered by an activity index created for this particular purpose. Due to the formulation of the question, pure subjective data were not considered. With regard to the social data, the two samples can very well be compared with other epidemiological studies. For the group of Crohn-patients, a significant correlation between psychosocial stress and a subsequent increased disease activity was demonstrated. Surprisingly, the group of patients with ulcerative colitis did not show this correlation.
以下研究探讨了慢性炎症性肠病患者心理社会压力与疾病活动度之间的相关性。70例克罗恩病患者和44例溃疡性结肠炎患者参与了本研究。使用一份用于记录生活变化事件的清单，询问了过去24个月的心理社会生活事件。疾病活动度通过为此特定目的创建的活动指数进行记录。由于问题的表述方式，未考虑纯粹的主观数据。就社会数据而言，这两个样本与其他流行病学研究具有很好的可比性。对于克罗恩病患者组，心理社会压力与随后疾病活动度增加之间存在显著相关性。令人惊讶的是，溃疡性结肠炎患者组未显示出这种相关性。
