von Wietersheim J, Overbeck A, Kiel K, Köhler T, Jantschek G, Feiereis H
Klinik für Psychosomatik und Psychotherapie, Medizinischen Universität zu Lübeck.
Psychother Psychosom Med Psychol. 1994 Feb;44(2):58-64.
This study examined whether life event stress under general or more specific conditions (fear of separation, feeling of being under pressure, feeling of being caught between two quarreling parties, separation experiences) contribute to the aggravation of inflammatory bowel disease. Firstly, 51 patients with ulcerative colitis, 57 patients with Crohn's disease, and 60 controls were compared in terms of these variables. In addition, the IBD patients filled out questionnaires regarding life events, the specific psychological conditions mentioned above, and their symptoms several times in the three years after the first measurement. By means of group comparisons and intraindividual correlations between relapse precipitating life events and illness activity, only feelings of being under pressure showed a modest correlation to the disease activity. We conclude that the variables in question have little influence on the beginning of the relapse.
本研究探讨了一般或更特定条件下的生活事件压力（害怕分离、压力感、夹在两个争吵方之间的感觉、分离经历）是否会导致炎症性肠病加重。首先，对51例溃疡性结肠炎患者、57例克罗恩病患者和60名对照者在这些变量方面进行了比较。此外，炎症性肠病患者在首次测量后的三年里多次填写了关于生活事件、上述特定心理状况及其症状的问卷。通过组间比较以及复发诱发生活事件与疾病活动之间的个体内相关性分析，仅压力感与疾病活动呈适度相关。我们得出结论，所讨论的这些变量对复发的起始影响很小。
