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经阴道分娩的低风险早产儿:胎儿酸中毒及6岁时的结局

Vaginally born low-risk preterm infants: fetal acidosis and outcome at 6 years of age.

作者信息

Holmqvist P, Plevén H, Svenningsen N W

机构信息

Department of Paediatrics, University Hospital, Lund, Sweden.

出版信息

Acta Paediatr Scand. 1988 Sep;77(5):638-41. doi: 10.1111/j.1651-2227.1988.tb10722.x.

DOI:10.1111/j.1651-2227.1988.tb10722.x
PMID:3201969
Abstract

In a population of vaginally born low-risk preterm infants fetal acidosis (scalp pH less than 7.20) was found in 50% (6 out of 12) of infants of 29-33 weeks' gestational age (Group I) and in 9% (2 of 22) infants of 34-36 weeks' gestational age (Group II). At 6-7 years of age the children underwent a neurodevelopmental examination including a Griffith test. Five out of 6 Group I infants with fetal acidosis and 10 out of 20 Group II infants without fetal acidosis had minor or moderate neurodevelopmental problems. On the Griffith test Group II infants scored below Group I with more coordination and fine motor problems on the tested subscales. Fetal acidosis was more common in very preterm infants but cannot be used per se as a reliable indicator of long-term outcome.

摘要

在一组经阴道分娩的低风险早产儿中,胎龄为29 - 33周的婴儿(第一组)中有50%(12例中的6例)出现胎儿酸中毒(头皮pH值低于7.20),胎龄为34 - 36周的婴儿(第二组)中有9%(22例中的2例)出现胎儿酸中毒。在6至7岁时,这些儿童接受了包括格里菲斯测试在内的神经发育检查。第一组中6例有胎儿酸中毒的婴儿中有5例,第二组中20例无胎儿酸中毒的婴儿中有10例存在轻度或中度神经发育问题。在格里菲斯测试中,第二组婴儿的得分低于第一组,在测试的子量表上存在更多协调和精细运动问题。胎儿酸中毒在极早产儿中更为常见,但本身不能作为长期预后的可靠指标。

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引用本文的文献

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Outcomes of Medically Indicated Preterm Births Differ by Indication.医学指征性早产的结局因指征而异。
Am J Perinatol. 2018 Jul;35(8):758-763. doi: 10.1055/s-0037-1615792. Epub 2017 Dec 29.
2
Abnormal cerebral haemodynamics in perinatally asphyxiated neonates related to outcome.围产期窒息新生儿的脑血流动力学异常与预后的关系。
Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2):F110-5. doi: 10.1136/fn.81.2.f110.