Albonette-Felicio Thiago, Rangel Gustavo G, Martinéz-Pérez Rafael, Hardesty Douglas A, Carrau Ricardo L, Prevedello Daniel M
Department of Neurological Surgery, The Ohio State University, The Wexner Medical Center, N-1049 Doan Hall, 410 W. 10th Avenue, Columbus, OH, 43210-1240, USA.
Anatomy Laboratory Toward Visuospatial Surgical Innovations in Otolaryngology and Neurosurgery (ALT-VISION), Graves Hall Building, 333 W 10th Avenue - Room 2167 L, Columbus, OH, 43210, USA.
J Neurooncol. 2020 Dec;150(3):429-436. doi: 10.1007/s11060-020-03413-y. Epub 2020 Feb 4.
Anterior skull base (ASB) malignancies are rare entities characterized by delayed diagnosis and comprise a variety of distinct histological types. Their treatment involves clinical and surgical management, with the latter encompassing open and, more recently, endoscopic approaches. The craniofacial resection, as an open approach, has revolutionized the treatment of such diseases and is the gold standard, although significant morbidity and facial scars are a shortcoming. Seeking a less invasive alternative, many surgeons have approached these pathologies using the endoscopic endonasal approach, with the theoretical advantage of reduced morbidity and no facial scars. In this manuscript, we aim to review the current state-of-art in the surgical management of the ASB malignancies. As such, indications, limitations and future perspectives of different surgical techniques are discussed.
前颅底（ASB）恶性肿瘤是罕见的疾病，其特点是诊断延迟，且包含多种不同的组织学类型。其治疗涉及临床和手术管理，后者包括开放手术，以及最近出现的内镜手术方法。颅面切除术作为一种开放手术方法，彻底改变了此类疾病的治疗方式，是金标准，尽管存在显著的发病率和面部瘢痕等缺点。为寻求侵入性较小的替代方法，许多外科医生采用内镜鼻内入路来处理这些病变，其理论优势是发病率降低且无面部瘢痕。在本手稿中，我们旨在综述ASB恶性肿瘤手术管理的当前技术水平。因此，将讨论不同手术技术的适应证、局限性和未来前景。
