Rios-Lugo María Judith, Madrigal-Arellano Casandra, Gaytán-Hernández Darío, Hernández-Mendoza Héctor, Romero-Guzmán Elizabeth Teresita
Unidad de Posgrado, Facultad de Enfermería y Nutrición, UASLP, Avda. Niño Artillero 130, CP 78210, San Luis Potosí, S.L.P., Mexico.
Sección de Medicina Molecular y Traslacional, Centro de Investigación en Ciencias de Salud y Biomedicina. UASLP, Avda Sierra Leona 550, CP 78210, San Luis, S.L.P., Mexico.
Biol Trace Elem Res. 2020 Nov;198(1):51-57. doi: 10.1007/s12011-020-02060-8. Epub 2020 Feb 5.
Low levels of zinc (Zn) have adverse effects on physiological and metabolic functions in humans, especially in processes linked with obesity. In this work, serum Zn levels and their associations with biochemical parameters (glucose, triglycerides, and total cholesterol), sex, and body mass index (BMI) were determined. The distribution of the study sample by sex was homogeneous: 52.6% were women and 47.4% were men. Women had higher BMI and Zn levels (normal weight and obesity) than men, but the differences in BMI and serum Zn levels by sex were not significant (p > 0.05). Nevertheless, the results obtained showed a decrease in serum Zn levels in overweight and obese individuals (p < 0.05) and a negative correlation between BMI and serum Zn levels (r = - 0.663 and p < 0.001); additionally, a significant correlation was identified between cholesterol and triglyceride values (r = 0.493 and p < 0.001). In conclusion, this study demonstrated decreased serum Zn levels in overweight and obese individuals.
锌（Zn）水平过低会对人体的生理和代谢功能产生不利影响，尤其是在与肥胖相关的过程中。在本研究中，测定了血清锌水平及其与生化参数（葡萄糖、甘油三酯和总胆固醇）、性别和体重指数（BMI）的关联。研究样本按性别分布均匀：52.6%为女性，47.4%为男性。女性的BMI和锌水平（正常体重和肥胖者）高于男性，但性别在BMI和血清锌水平上的差异不显著（p>0.05）。然而，所得结果显示超重和肥胖个体的血清锌水平降低（p<0.05），且BMI与血清锌水平呈负相关（r=-0.663，p<0.001）；此外，胆固醇与甘油三酯值之间存在显著相关性（r=0.493，p<0.001）。总之，本研究表明超重和肥胖个体的血清锌水平降低。
