Department of Mechanical Engineering , Korea Advanced Institute of Science and Technology , 291, Daehak-ro , Yuseong-gu, Daejeon 34141 , Republic of Korea.
RF Medical. Co. Ltd. , 254, Beotkkot-ro , Geumcheon-gu, Seoul 08511 , Republic of Korea.
ACS Sens. 2020 Feb 28;5(2):481-489. doi: 10.1021/acssensors.9b02260. Epub 2020 Feb 19.
In this research, an ultrathin, biocompatible, and flexible pressure sensor with a wide pressure range has been developed and applied in biomedical applications. The pressure sensing mechanism is based on the variation of contact resistance between an electrode and a three-dimensional microstructured polyimide/carbon nanotube composite film. The sensor has a thickness of about 31.3 μm, a maximum sensitivity of 41.0 MPa, and a sensing range of 10-500 kPa. Moreover, in situ temperature measurement by an integrated resistive temperature detector enables data correction for varying temperature conditions. In order to show the advantages of the fabricated sensor, it is attached to the human body and integrated with the surface of a radiofrequency ablation (RFA) needle with small radius of curvature. In the experiments, the proposed pressure sensor measured subtle pressure levels (pulse pressure) and high pressure levels (fingertip pressure) without losing conformal contact with the skin. In addition, when the pressure-sensor-integrated RFA needle was inserted into a bovine liver, successful detection of steam popping phenomenon was observed.
在这项研究中，我们开发并应用了一种超薄、生物相容且灵活的压力传感器，其具有较宽的压力范围。压力传感机制基于电极和三维微结构化聚酰亚胺/碳纳米管复合薄膜之间接触电阻的变化。该传感器的厚度约为 31.3μm，最大灵敏度为 41.0MPa，感应范围为 10-500kPa。此外，通过集成的电阻式温度探测器进行原位温度测量，可实现对不同温度条件下数据的修正。为了展示所制传感器的优势，我们将其附着在人体上，并与具有小曲率半径的射频消融（RFA）针的表面集成。在实验中，所提出的压力传感器在不失去与皮肤的贴合接触的情况下，成功测量了细微的压力水平（脉压）和较高的压力水平（指尖压力）。此外，当将压力传感器集成的 RFA 针插入牛肝时，成功观察到了蒸汽爆裂现象。
