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27匹母马接受双侧站立式腹腔镜卵巢切除术前后的卵巢组织病理学、内分泌学分析及行为改变

Ovarian histopathology, pre- and post-operative endocrinological analysis and behavior alterations in 27 mares undergoing bilateral standing laparoscopic ovariectomy.

作者信息

Devick Ian F, Leise Britta S, McCue Patrick M, Rao Sangeeta, Hendrickson Dean A

机构信息

Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).

出版信息

Can Vet J. 2020 Feb;61(2):181-186.

PMID:32020939
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6973214/
Abstract

Determining if ovariectomy will abolish unwanted behaviors can be challenging in mares without ultrasonographic ovarian abnormalities and/or endocrine values not consistent with a granulosa cell tumor. The objective of the study was to identify mares that have a positive improvement in unwanted behaviors after elective standing laparoscopic ovariectomy and to determine if the change is associated with any pre- and post-operative endocrine profiles and/or with ovarian histological findings. During the study period 27 mares underwent a bilateral standing laparoscopic ovariectomy. Pre- and post-operative questionnaires and endocrine profiles, along with ovarian histopathology were performed and data were analyzed. Eighty-nine percent of clients were satisfied with the change in behavior after surgery. There were no significant associations between specific elevated hormones or absent luteal tissue with any specific unwanted behaviors. Pre-operative endocrine values were not predictive of post-operative owner satisfaction but bilateral ovariectomy for the treatment of unwanted behaviors in mares had a high likelihood of achieving owner satisfaction.

摘要

对于没有超声检查发现卵巢异常和/或内分泌值与颗粒细胞瘤不一致的母马,确定卵巢切除术是否能消除不良行为可能具有挑战性。本研究的目的是识别在择期站立式腹腔镜卵巢切除术后不良行为有积极改善的母马,并确定这种变化是否与术前和术后的内分泌谱和/或卵巢组织学发现有关。在研究期间,27匹母马接受了双侧站立式腹腔镜卵巢切除术。进行了术前和术后问卷调查、内分泌谱分析以及卵巢组织病理学检查,并对数据进行了分析。89%的客户对手术后行为的改变感到满意。特定激素升高或黄体组织缺失与任何特定的不良行为之间没有显著关联。术前内分泌值不能预测术后主人的满意度,但双侧卵巢切除术治疗母马的不良行为很有可能使主人满意。

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Can Vet J. 2018 Mar;59(3):261-266.
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Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare.马血清中抗 Müllerian 激素测定的生物学和临床意义。
Theriogenology. 2011 Nov;76(8):1393-403. doi: 10.1016/j.theriogenology.2011.06.008. Epub 2011 Jul 28.
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Expression of anti-Müllerian hormone (AMH) in equine granulosa-cell tumors and in normal equine ovaries.抗缪勒管激素(AMH)在马颗粒细胞瘤及正常马卵巢中的表达。
Theriogenology. 2008 Oct 1;70(6):968-77. doi: 10.1016/j.theriogenology.2008.05.059. Epub 2008 Jul 3.
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Acta Oncol. 2008;47(3):406-12. doi: 10.1080/02841860701592400. Epub 2007 Sep 24.
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