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鼻病毒相关性扩张型心肌病

Rhinovirus-associated dilated cardiomyopathy.

作者信息

Chow Jeffrey, Murphy Joey, Subedi Ashish, Jyothidasan Amudhan

机构信息

Cape Fear Valley Medical Center, Internal Medicine Resident, 1638 Owen Drive, Fayetteville, North Carolina, United States.

University of Campbell, Medical Student, 1 Fort Bragg, Fort Bragg, North Carolina, United States.

出版信息

IDCases. 2020 Jan 14;19:e00702. doi: 10.1016/j.idcr.2020.e00702. eCollection 2020.

DOI:10.1016/j.idcr.2020.e00702
PMID:32021801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992979/
Abstract

Rhinovirus is the main cause of the common cold. There is little to no published literature of rhinoviral associated myocarditis. We report a rare case of rhinovirus infection in a patient with myocarditis leading to dilated cardiomyopathy. Infection is an established cause of myocarditis. Prodromal "flu-like" symptoms in a young patient with unexplained heart failure should raise concern for viral myocarditis. Diagnosis is often made by clinical presentation and not by endomyocardial biopsy due to invasiveness. Polymerase chain reaction is a rapid test that supports the diagnosis and may elucidate the role of the virus in myocarditis. Defining causes and mechanisms leading to this severe cardiovascular condition may prove critical to targeted therapy. Physician should be aware that rhinovirus as a possible pathogen for severe myocarditis and dilated cardiomyopathy.

摘要

鼻病毒是普通感冒的主要病因。关于鼻病毒相关性心肌炎的已发表文献极少。我们报告了1例罕见的鼻病毒感染病例,该患者患有心肌炎并导致扩张型心肌病。感染是心肌炎的既定病因。年轻患者出现前驱“流感样”症状且伴有不明原因的心力衰竭时,应警惕病毒性心肌炎。诊断通常依据临床表现,而非因具有侵入性的心内膜心肌活检。聚合酶链反应是一种快速检测方法,可辅助诊断并可能阐明病毒在心肌炎中的作用。明确导致这种严重心血管疾病的病因和机制可能对靶向治疗至关重要。医生应意识到鼻病毒可能是严重心肌炎和扩张型心肌病的病原体。

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JMM Case Rep. 2018 Feb 1;5(9):e005139. doi: 10.1099/jmmcr.0.005139. eCollection 2018 Sep.
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Pathogen-driven treatment strategy in new onset dilated cardiomyopathy. Impact on ventricular function and clinical outcome.新发扩张型心肌病的病原体驱动治疗策略。对心室功能和临床结局的影响。
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