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大量膝关节置换术后患者的性期望未得到满足:一项前瞻性研究。

A High Proportion of Patients Have Unfulfilled Sexual Expectations After TKA: A Prospective Study.

机构信息

R. T. E. Harmsen, M. G. J. Gademan, R. G. H. H. Nelissen, Department of Orthopaedics, Leiden University Medical Center, Leiden the Netherlands.

T. M. Haanstra, Orthopedic Unit, Radboud UMC, Nijmegen and the Association of Dutch Burns Centres (TMH).

出版信息

Clin Orthop Relat Res. 2020 Sep;478(9):2004-2016. doi: 10.1097/CORR.0000000000001003.

Abstract

BACKGROUND

Most patients have high expectations about restoration of the knee function after TKA, expecting a more active life after retirement. However, 20% to 30% of patients report that their expectations are not met postoperatively. Among those unmet expectations may be the anticipation to engage in sexual activity after surgery, but few studies have evaluated sexual activity after arthroplasty.

QUESTIONS/PURPOSES: In this study, our purposes were (1) to evaluate the anticipation and the fulfillment of sexual activity after TKA in men and women, and (2) to identify prognostic factors for the fulfillment of anticipated postoperative sexual activity.

METHODS

This was a prospective, multicenter study of all 1371 patients scheduled for TKA between June 2012 and July 2015. The study was part of the Longitudinal Leiden Orthopaedics Outcomes of Osteoarthritis Study (LOAS). After screening according to LOAS inclusion criteria, 1213 respondents remained. Our primary study endpoint was whether sexual expectations were met 1 year after TKA; we used the sexual-activity-expectation question from the Hospital for Special Surgery (HSS) Knee Replacement Expectations Survey, which allows the patient to score the result on a 5-point scale. To assess postoperative fulfillment of sexual activity 1 year after TKA, we asked the patient to score the current status of sexual activity on the same 5-point scale: 1 (back to normal), 2 (large improvement), 3 (moderate improvement), 4 (slight improvement), and 5 (does not apply). Patients with incomplete data on the preoperative expectation- and postoperative fulfillment-question of sexual activity were excluded, leaving 71% (866 of 1213) patients for analysis. The difference between the pre- and postoperative scores determined whether expectations of sexual activity were unfulfilled (lower than expected) or fulfilled/exceeded (neutral or higher than expected). Pre- and postoperatively, the Knee Injury and Osteoarthritis Outcome Score (KOOS), the Short Form-12 Mental and Physical Component Summary scores (SF-12 MCS and SF-12 PCS), the EuroQoL-5 Dimensions (EQ-5D), and the EQ-5D VAS scale were used. Multivariate regression models were used for analysis.

RESULTS

Preoperatively, 54% patients (467 of 866) anticipated postoperative sexual activity after recovery from surgery. Both genders showed that the proportion who anticipated "back to normal" sexual activity decreased with higher age. Likewise, postoperative fulfillment of anticipated sexual activity was found in 58% (111 of 191 for men; 159 of 276 for women). Younger women (younger than 65 years of age) experienced fulfillment more often compared with younger men. A positive postoperative change in functional and health status was associated with fulfilled/exceeded scores of patients anticipating postoperative sexual activity. A better preoperative health status, the EQ-5D VAS score (odds ratio [OR] 1.02 [95% CI 1.01 to 1.03]; p = 0.006), was associated with a higher likelihood of fulfillment of anticipated postoperative sexual activity.

CONCLUSION

In both men and women, two of five patients who anticipated postoperative sexual activity indicated that their expectation of sexual activity was not met 1 year after TKA. These patients had worse functional recovery scores compared with patients who achieved the anticipated level of sexual activity. The latter is associated with functional recovery. Surgeons should be aware that many patients anticipate restoration of normal sexual activity, and that this may be the expectation for patients of all ages and for women and men alike. The results underscore the need for more qualitative research to understand this topic in greater depth.

LEVEL OF EVIDENCE

Level II, therapeutic study.

摘要

背景

大多数患者对 TKA 后膝关节功能的恢复抱有很高的期望,期望在退休后过上更积极的生活。然而,20%至 30%的患者报告说他们的期望在术后没有得到满足。在这些未满足的期望中,可能包括对手术后进行性行为的预期,但很少有研究评估过关节置换术后的性行为。

问题/目的:在这项研究中,我们的目的是(1)评估男性和女性 TKA 后对性行为的预期和实现,以及(2)确定预测预期术后性行为实现的预后因素。

方法

这是一项前瞻性、多中心研究,共纳入了 2012 年 6 月至 2015 年 7 月期间计划接受 TKA 的 1371 名患者。该研究是 Leiden 骨科关节炎研究(LOAS)的一部分。根据 LOAS 的纳入标准进行筛选后,仍有 1213 名受访者。我们的主要研究终点是 1 年后 TKA 后患者的性行为期望是否得到满足;我们使用了来自特殊外科医院(HSS)膝关节置换期望调查的性行为期望问题,该问题允许患者在 5 分制上对结果进行评分。为了评估 1 年后 TKA 后患者术后性行为的实现情况,我们要求患者在同一 5 分制上对当前性行为状况进行评分:1(恢复正常)、2(明显改善)、3(中度改善)、4(轻度改善)和 5(不适用)。排除了术前性行为期望和术后实现情况问题上数据不完整的患者,共有 71%(866 名患者中的 71%)的患者进行了分析。术前和术后评分之间的差异决定了性行为的期望是否未得到满足(低于预期)或得到满足/超过预期。术前和术后使用了膝关节损伤和骨关节炎结局评分(KOOS)、简短形式-12 精神和身体成分综合评分(SF-12 MCS 和 SF-12 PCS)、欧洲五维健康量表(EQ-5D)和 EQ-5D 视觉模拟量表(EQ-5D VAS)。采用多变量回归模型进行分析。

结果

术前,54%的患者(866 名患者中的 467 名)预计手术后恢复后会有性行为。两性都表明,预期“恢复正常”性行为的比例随着年龄的增长而降低。同样,术后实现预期性行为的比例为 58%(男性 191 名中的 111 名;女性 276 名中的 159 名)。年轻女性(年龄小于 65 岁)比年轻男性更常经历实现。术后功能和健康状况的积极变化与预期术后性行为实现的患者的得分相符。更好的术前健康状况、EQ-5D VAS 评分(比值比[OR]1.02[95%CI 1.01 至 1.03];p=0.006)与更高的可能性相关预期术后性行为的实现。

结论

在男性和女性中,五分之二的预期术后性行为的患者表示,他们对性行为的期望在 TKA 后 1 年没有得到满足。这些患者的功能恢复评分比实现预期性行为水平的患者差。后者与功能恢复有关。外科医生应该意识到,许多患者期望恢复正常的性行为,而且这可能是所有年龄段患者的期望,也是男性和女性的期望。研究结果强调了需要进行更多的定性研究,以更深入地了解这一主题。

证据水平

二级,治疗性研究。

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