• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

含有偶氮苯、MEOMA和OEGMA的结构明确的双光响应和热响应性棒-线圈嵌段共聚物。

Well-Defined Dual Light- and Thermo-Responsive Rod-Coil Block Copolymers Containing an Azobenzene, MEOMA and OEGMA.

作者信息

Park Changjun, Heo Jaewon, Lee Jinhee, Kim Taehyoung, Kim Sang Youl

机构信息

Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.

出版信息

Polymers (Basel). 2020 Feb 1;12(2):284. doi: 10.3390/polym12020284.

DOI:10.3390/polym12020284
PMID:32024115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7077463/
Abstract

Here we report the dual light- and thermo-responsive behavior of well-defined rod-coil block copolymers composed of an azobenzene unit, 2-(2-methoxyethoxy)ethyl methacrylate (MEOMA) and oligo(ethylene glycol) methacrylate (OEGMA). Azobenzene-containing rigid rod blocks prepared by chain growth condensation polymerization of the azobenzene containing monomer were used as a macroinitiator of atom transfer radical polymerization (ATRP) after attaching an α-bromoisobutyryl group as an end group. Synthesis of well-defined rod-coil block copolymers with different coil block lengths was achieved by copolymerization of MEOMA and OEGMA monomers. The synthesized polymers exhibited amphiphilic properties and polymeric micelles were formed in aqueous solution. The light-responsive behaviors of azobenzene moieties, photoisomerization by irradiation of light, and thermo-responsive behaviors of P(MEOMA--OEGMA) coil blocks, aggregation by increment of temperature over lower critical solution temperature, were investigated. A dual stimuli-responsive behavior of the rod-coil block copolymers was observed when exposed to light and heat.

摘要

在此，我们报道了由偶氮苯单元、甲基丙烯酸2-(2-甲氧基乙氧基)乙酯(MEOMA)和甲基丙烯酸寡聚(乙二醇)酯(OEGMA)组成的结构明确的棒-线圈嵌段共聚物的光热双重响应行为。通过含偶氮苯单体的链增长缩聚反应制备的含偶氮苯刚性棒段，在连接α-溴异丁酰基作为端基后用作原子转移自由基聚合(ATRP)的大分子引发剂。通过MEOMA和OEGMA单体的共聚反应，实现了具有不同线圈段长度的结构明确的棒-线圈嵌段共聚物的合成。合成的聚合物表现出两亲性，在水溶液中形成聚合物胶束。研究了偶氮苯部分的光响应行为，即光照引发的光异构化，以及P(MEOMA-OEGMA)线圈段的热响应行为，即温度升高超过低临界溶液温度时的聚集。当暴露于光和热时，观察到棒-线圈嵌段共聚物的双重刺激响应行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e2/7077463/607e48347ad8/polymers-12-00284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e2/7077463/d5606d431c2c/polymers-12-00284-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e2/7077463/607e48347ad8/polymers-12-00284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e2/7077463/d5606d431c2c/polymers-12-00284-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e2/7077463/607e48347ad8/polymers-12-00284-g001.jpg

相似文献

1
Well-Defined Dual Light- and Thermo-Responsive Rod-Coil Block Copolymers Containing an Azobenzene, MEOMA and OEGMA.含有偶氮苯、MEOMA和OEGMA的结构明确的双光响应和热响应性棒-线圈嵌段共聚物。
Polymers (Basel). 2020 Feb 1;12(2):284. doi: 10.3390/polym12020284.
2
Novel Temperature/Reduction Dual-Stimulus Responsive Triblock Copolymer [P(MEOMA-- OEGMA)--PLLA-SS-PLLA--P(MEOMA--OEGMA)] via a Combination of ROP and ATRP: Synthesis, Characterization and Application of Self-Assembled Micelles.通过开环聚合和原子转移自由基聚合相结合制备新型温度/还原双刺激响应性三嵌段共聚物[P(MEOMA-OEGMA)-PLLA-SS-PLLA-P(MEOMA-OEGMA)]：自组装胶束的合成、表征及应用
Polymers (Basel). 2020 Oct 26;12(11):2482. doi: 10.3390/polym12112482.
3
Thermo-responsive drug release from self-assembled micelles of brush-like PLA/PEG analogues block copolymers.从刷状聚乳酸/聚乙二醇类似物嵌段共聚物的自组装胶束中实现热响应性药物释放。
Int J Pharm. 2015 Aug 1;491(1-2):152-61. doi: 10.1016/j.ijpharm.2015.06.020. Epub 2015 Jun 18.
4
Magnetothermally responsive star-block copolymeric micelles for controlled drug delivery and enhanced thermo-chemotherapy.磁热响应星型嵌段共聚物胶束用于控制药物释放和增强热化疗。
Nanoscale. 2015 Jun 7;7(21):9655-63. doi: 10.1039/c5nr00642b.
5
Novel Amphiphilic, Biodegradable, Biocompatible, Thermo-Responsive ABA Triblock Copolymers Based on PCL and PEG Analogues via a Combination of ROP and RAFT: Synthesis, Characterization, and Sustained Drug Release from Self-Assembled Micelles.基于聚己内酯（PCL）和聚乙二醇（PEG）类似物，通过开环聚合（ROP）与可逆加成-断裂链转移聚合（RAFT）相结合制备的新型两亲性、可生物降解、生物相容性良好、具有热响应性的ABA三嵌段共聚物：合成、表征及自组装胶束的药物缓释性能
Polymers (Basel). 2018 Feb 22;10(2):214. doi: 10.3390/polym10020214.
6
Synthesis of thermo-responsive polymers with both tunable UCST and LCST.合成具有可调节上临界溶解温度 (UCST) 和下临界溶解温度 (LCST) 的温敏聚合物。
Macromol Rapid Commun. 2011 Apr 19;32(8):660-4. doi: 10.1002/marc.201000713. Epub 2011 Mar 7.
7
Amphiphilic multiarm star block copolymer-based multifunctional unimolecular micelles for cancer targeted drug delivery and MR imaging.基于两亲性多臂星型嵌段共聚物的多功能单分子胶束用于癌症靶向药物递送和磁共振成像。
Biomaterials. 2011 Sep;32(27):6595-605. doi: 10.1016/j.biomaterials.2011.05.049. Epub 2011 Jun 12.
8
Responsive polymers-based dual fluorescent chemosensors for Zn2+ ions and temperatures working in purely aqueous media.基于响应性聚合物的双荧光化学传感器，用于在纯水性介质中检测 Zn2+ 离子和温度。
Anal Chem. 2011 Apr 1;83(7):2775-85. doi: 10.1021/ac200095f. Epub 2011 Mar 2.
9
Amphiphilic graft copolymers with ethyl cellulose backbone: Synthesis, self-assembly and tunable temperature-CO2 response.具有乙基纤维素主链的两亲性接枝共聚物：合成、自组装和可调温 CO2 响应。
Carbohydr Polym. 2016 Jan 20;136:216-23. doi: 10.1016/j.carbpol.2015.09.052. Epub 2015 Sep 21.
10
Synthesis and Self-Assembly of Thermoresponsive Biohybrid Graft Copolymers Based on a Combination of Passerini Multicomponent Reaction and Molecular Recognition.基于帕斯基（Passerini）多组分反应和分子识别的组合的温敏性生物杂化接枝共聚物的合成与自组装。
Macromol Rapid Commun. 2021 Nov;42(21):e2100424. doi: 10.1002/marc.202100424. Epub 2021 Sep 20.

引用本文的文献

1
A Temperature/pH Double-Responsive and Physical Double-Crosslinked Hydrogel Based on PLA and Histidine.一种基于聚乳酸和组氨酸的温度/pH双响应性物理双交联水凝胶。
Gels. 2022 Sep 7;8(9):570. doi: 10.3390/gels8090570.
2
Synthesis and Properties of Hydrogels on Medical Titanium Alloy Surface by Modified Dopamine Adhesion.基于改性多巴胺粘附作用的医用钛合金表面水凝胶的合成与性能
Gels. 2022 Jul 22;8(8):458. doi: 10.3390/gels8080458.
3
Novel Temperature/Reduction Dual-Stimulus Responsive Triblock Copolymer [P(MEOMA-- OEGMA)--PLLA-SS-PLLA--P(MEOMA--OEGMA)] via a Combination of ROP and ATRP: Synthesis, Characterization and Application of Self-Assembled Micelles.

本文引用的文献

1
Chiral induction, modulation and locking in porphyrin based supramolecular assemblies with circularly polarized light.基于卟啉的超分子组装体中手性诱导、调控及利用圆偏振光进行锁定
Chem Commun (Camb). 2019 Apr 23;55(34):4953-4956. doi: 10.1039/c9cc01613a.
2
Control over hierarchy levels in the self-assembly of stackable nanotoroids.堆叠纳米环自组装中层次的控制。
J Am Chem Soc. 2012 Nov 7;134(44):18205-8. doi: 10.1021/ja308519b. Epub 2012 Oct 26.
3
Control over molecular motion using the cis-trans photoisomerization of the azo group.
通过开环聚合和原子转移自由基聚合相结合制备新型温度/还原双刺激响应性三嵌段共聚物[P(MEOMA-OEGMA)-PLLA-SS-PLLA-P(MEOMA-OEGMA)]：自组装胶束的合成、表征及应用
Polymers (Basel). 2020 Oct 26;12(11):2482. doi: 10.3390/polym12112482.
4
Stereocomplexation of Poly(Lactic acid) and Chemical Crosslinking of Ethylene Glycol Dimethacrylate (EGDMA) Double-Crosslinked Temperature/pH Dual Responsive Hydrogels.聚乳酸的立体复合以及乙二醇二甲基丙烯酸酯（EGDMA）的化学交联双交联温度/pH双重响应水凝胶
Polymers (Basel). 2020 Sep 25;12(10):2204. doi: 10.3390/polym12102204.
5
Development of Environmentally Friendly Atom Transfer Radical Polymerization.环境友好型原子转移自由基聚合的发展
Polymers (Basel). 2020 Aug 31;12(9):1987. doi: 10.3390/polym12091987.
利用偶氮基团的顺反光致异构化来控制分子运动。
Beilstein J Org Chem. 2012;8:1071-90. doi: 10.3762/bjoc.8.119. Epub 2012 Jul 12.
4
Temperature- and light-responsive smart polymer materials.温度和光响应智能高分子材料。
Chem Soc Rev. 2013 Sep 7;42(17):7468-83. doi: 10.1039/c2cs35191a.
5
Stimuli-responsive supramolecular polymeric materials.刺激响应超分子聚合物材料。
Chem Soc Rev. 2012 Sep 21;41(18):6042-65. doi: 10.1039/c2cs35091b. Epub 2012 May 22.
6
Photoinduced reversible transmittance modulation of rod-coil type diblock copolymers containing azobenzene in the main chain.含偶氮苯主链的棒-线嵌段共聚物的光致可逆透过率调制。
Chem Commun (Camb). 2012 Apr 4;48(27):3351-3. doi: 10.1039/c2cc17265h. Epub 2012 Feb 24.
7
Light-responsive block copolymers.光响应性嵌段共聚物。
Macromol Rapid Commun. 2010 Sep 15;31(18):1588-607. doi: 10.1002/marc.201000108. Epub 2010 May 20.
8
Azobenzene photoswitches for biomolecules.偶氮苯光开关用于生物分子。
Chem Soc Rev. 2011 Aug;40(8):4422-37. doi: 10.1039/c1cs15023e. Epub 2011 Apr 12.
9
Nanostructured functional materials prepared by atom transfer radical polymerization.通过原子转移自由基聚合制备的纳米结构功能材料。
Nat Chem. 2009 Jul;1(4):276-88. doi: 10.1038/nchem.257. Epub 2009 Jun 22.
10
Thermo- and light responsive micellation of azobenzene containing block copolymers.含偶氮苯的嵌段共聚物的温敏和光响应胶束化。
Chem Commun (Camb). 2010 Sep 28;46(36):6717-9. doi: 10.1039/c0cc01288b. Epub 2010 Aug 17.