Naghibi Hamid, Janssen Dennis, Van Tienen Tony, Van de Groes Sebastiaan, Van de Boogaard Ton, Verdonschot Nico
Robotics and Mechatronics Lab, University of Twente, Enschede, the Netherlands.
Radboud University Medical Center, Radboud Institute for Health Sciences, Orthopaedic Research Lab, 6525, GA, Nijmegen, the Netherlands.
Knee. 2020 Mar;27(2):384-396. doi: 10.1016/j.knee.2020.01.010. Epub 2020 Feb 2.
In ACL-reconstructed patients the postoperative knee biomechanics may differ from the intact knee biomechanical behavior which can alter knee kinematics and kinetics, and as a result lead to the progression of knee osteoarthritis. The aim of this study was to demonstrate the potential of finite element models to define the optimal choices in surgical parameters in terms of optimal graft positioning in combination with graft type in order to restore the kinematic and kinetic behavior of the knee as best as possible.
A workflow was proposed based on cadaveric experiments in order to restore the injured knee to a near normal physiological condition. Femoral and tibial graft insertion sites and graft fixation tension were optimized to obtain similar intact knee laxity, for three common single-bundle and one double-bundle reconstructions. To verify the success of the surgery with the variables calculated using the proposed workflow, a full walking cycle was simulated with the intact, ACL-ruptured, optimal ACL-reconstructed and non-optimal reconstructed knees.
Our results suggested that for patellar tendon and hamstring tendon grafts, anatomical positioning (fixation force: 40 N), and for quadriceps tendon graft, isometric positioning (fixation tension: 85 N) could recover the intact joint kinematics and kinetics. Also for double-bundle reconstruction, with the numerically calculated optimal insertion sites, both bundles needed 50-N fixation force.
With optimal graft positioning parameters, following the proposed workflow in this study, any of the single-bundle graft types and surgical techniques (single vs. double-bundle) may be used to acceptably recover the intact knee joint biomechanical behavior.
在进行前交叉韧带重建的患者中,术后膝关节生物力学可能与正常膝关节的生物力学行为不同,这会改变膝关节的运动学和动力学,进而导致膝关节骨关节炎的进展。本研究的目的是证明有限元模型在确定手术参数方面的潜力,即在结合移植物类型的情况下确定最佳移植物位置,以尽可能恢复膝关节的运动学和动力学行为。
基于尸体实验提出了一种工作流程,以便将受伤的膝关节恢复到接近正常的生理状态。对于三种常见的单束和一种双束重建,优化股骨和胫骨移植物插入部位以及移植物固定张力,以获得与正常膝关节相似的松弛度。为了用使用所提出的工作流程计算出的变量验证手术的成功性,对完整、前交叉韧带断裂、最佳前交叉韧带重建和非最佳重建的膝关节进行了完整步行周期的模拟。
我们的结果表明,对于髌腱和腘绳肌腱移植物,解剖学定位(固定力:40 N),对于股四头肌肌腱移植物,等长定位(固定张力:85 N)可以恢复完整关节的运动学和动力学。同样对于双束重建,通过数值计算出的最佳插入部位,两束都需要50 N的固定力。
采用最佳的移植物定位参数,遵循本研究中提出的工作流程,任何一种单束移植物类型和手术技术(单束与双束)都可用于可接受地恢复完整膝关节的生物力学行为。