Lui Yuk Fai, Ip Wing Yuk, Shad Momina, Chan Hui Yi
Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong.
J Orthop. 2020 Jan 18;20:105-110. doi: 10.1016/j.jor.2020.01.018. eCollection 2020 Jul-Aug.
A group of chickens was employed as animal model for evaluation of osteointegration, stability and to a lesser extent, functional recovery potential of a newly designed human finger joint prosthesis under long term implantation. Mechanical and Histological test was conducted. Results in our study suggest that while chicken interphalangeal joint could be a potential model for evaluating surgical operation and osteointegration of human finger joint prosthesis, the effectiveness of evaluation in certain areas are far from ideal especially in functional and mechanical evaluation of the prosthesis. Nevertheless, it is suggested that chicken interphalangeal joint can still be a potential model for evaluating new human finger joint prosthesis if enough anchoring and stabilization could be provided because of the similarity in anatomical structure.
一组鸡被用作动物模型，以评估一种新设计的人类手指关节假体在长期植入下的骨整合、稳定性以及在较小程度上的功能恢复潜力。进行了力学和组织学测试。我们的研究结果表明，虽然鸡指间关节可能是评估人类手指关节假体手术操作和骨整合的潜在模型，但在某些方面的评估效果远不理想，尤其是在假体的功能和力学评估方面。然而，由于解剖结构相似，如果能提供足够的锚固和稳定性，建议鸡指间关节仍可作为评估新型人类手指关节假体的潜在模型。
