Department of Radiology, The First Hospital of Jilin University, No.71 XinMin Street, Changchun, 130021, China.
World J Surg Oncol. 2020 Feb 7;18(1):32. doi: 10.1186/s12957-020-1810-6.
Unilateral absence of pulmonary artery (UAPA) is a rare congenital disease of pulmonary circulation, which is often accompanied by other cardiovascular anomalies. Infrequently, it may remain undiagnosed until adulthood. More rarely, it is to be found with lung cancer in the ipsilateral or contralateral lung simultaneously.
A 56-year-old man with complaints of intermittent left chest pain for 2 months was referred to our hospital. Chest computed tomography(CT) revealed a cavitary lesion measuring 5.5 cm × 5.7 cm in the superior segment of the left lower lobe. Absence of left pulmonary artery and right-sided aortic arch were found on chest computed tomography angiography (CTA). The tumor was successfully removed via left pneumonectomy, and postoperative histopathology showed that the tumor was a squamous cell carcinoma (T2bN1). At a postoperative 24-month follow-up, the patient was free of disease and no evidence of recurrence or metastasis. Based on literature review, this is the ninth case of lung cancer in UAPA patients.
Lung cancer and UAPA occurred ipsilaterally in 66.7% of these cases (6/9), including the present case. For those patients who occurred contralaterally, surgical treatment may be more challenging. CT and CTA could provide an accurate diagnosis for this disease entity. Identification and recognition of this rare and special disease entity may facilitate timely diagnosis and appropriate treatment.
肺动脉单侧缺如（UAPA）是一种罕见的肺循环先天性疾病，常伴有其他心血管异常。它很少在成年后才被诊断出来。更罕见的是，同侧或对侧肺部同时并发肺癌。
一名 56 岁男性，因间歇性左侧胸痛 2 个月就诊。胸部 CT 显示左肺下叶上段有一个 5.5cm×5.7cm 的空洞病变。胸部 CT 血管造影（CTA）显示左肺动脉缺失和右侧主动脉弓。通过左肺切除术成功切除肿瘤，术后组织病理学显示肿瘤为鳞状细胞癌（T2bN1）。术后 24 个月随访时，患者无疾病，无复发或转移证据。根据文献复习，这是第 9 例 UAPA 患者合并肺癌。
同侧发生肺癌和 UAPA 的占 66.7%（6/9），包括本病例。对于对侧发生的患者，手术治疗可能更具挑战性。CT 和 CTA 可以对此疾病实体提供准确的诊断。识别这种罕见且特殊的疾病实体可能有助于及时诊断和适当治疗。
