School of Life Science and Engineering, Foshan University, Foshan 528231, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Poult Sci. 2020 Feb;99(2):744-751. doi: 10.1016/j.psj.2019.10.043. Epub 2019 Nov 27.
Lycium barbarum polysaccharides (LBP) are considered to be the major bioactive components of L. barbarum and have been widely used as a well-known traditional Chinese medicine and functional food because of their various biological activities. However, no published research has investigated the use of LBP as a feed additive in broilers. The objective of this study was to evaluate the effects of dietary LBP supplementation on the growth performance, digestive enzyme activities, antioxidant status, and immunity of broiler chickens. A total of 256 one-day-old Arbor Acres male broiler chicks were randomly allotted into 4 groups, with 8 replicates of 8 birds each, and were fed a corn-soybean meal-type basal diet supplemented without (control group) or with 1,000, 2,000, or 4,000 mg/kg LBP for 6 wk. The results showed that compared with the control diet, a significant increase in ADG (P < 0.05) during the grower and overall periods was observed in chickens fed the basal diet supplemented with 2,000 mg/kg LBP, whereas supplementation with 1,000 or 2,000 mg/kg LBP decreased feed-to-gain ratio (P < 0.05) during the starter period. The inclusion of LBP in the broiler diets increased overall amylase, lipase, and protease activities (P < 0.05). Supplementation with increasing levels of dietary LBP increased the activities of superoxide dismutase and glutathione peroxidase but decreased malondialdehyde content in the serum and liver (P < 0.05). Broilers fed with LBP-containing diets exhibited higher serum IgG and IgA concentrations (P < 0.05) than the broilers fed with the control diet. Serum tumor necrosis factor α and IL-4 concentrations were significantly elevated in the group fed 2,000 mg/kg LBP compared with the control group (P < 0.05). Broilers fed diets supplemented with LBP showed linear (P < 0.05) and quadratic (P < 0.05) increases in serum IL-6 and interferon gamma concentrations. The results indicated that dietary LBP supplementation can improve growth performance, digestive enzyme activities, antioxidant capacity, and immune function of broilers. In conclusion, LBP may be used as a promising feed additive for broilers, and a supplementation level of 2,000 mg/kg LBP in the broiler diet is recommended.
枸杞多糖（LBP）被认为是枸杞的主要生物活性成分，由于其具有多种生物活性，已被广泛用作一种著名的中药和功能性食品。然而，目前尚无研究报道将 LBP 用作肉鸡的饲料添加剂。本研究旨在评估日粮补充 LBP 对肉鸡生长性能、消化酶活性、抗氧化状态和免疫力的影响。将 256 只 1 日龄 Arbor Acres 雄性肉鸡随机分为 4 组，每组 8 个重复，每个重复 8 只鸡，分别饲喂基础玉米-豆粕型日粮，不添加（对照组）或添加 1000、2000 或 4000 mg/kg LBP，试验期为 6 周。结果表明，与对照组相比，基础日粮中添加 2000 mg/kg LBP 显著提高了生长期和整个试验期肉鸡的 ADG（P<0.05），而添加 1000 或 2000 mg/kg LBP 降低了生长期的料重比（P<0.05）。在肉鸡日粮中添加 LBP 提高了淀粉酶、脂肪酶和蛋白酶的总活性（P<0.05）。随着日粮中 LBP 添加水平的增加，超氧化物歧化酶和谷胱甘肽过氧化物酶的活性增加，血清和肝脏中丙二醛含量降低（P<0.05）。饲喂含 LBP 日粮的肉鸡血清 IgG 和 IgA 浓度高于对照组（P<0.05）。与对照组相比，饲喂 2000 mg/kg LBP 的肉鸡血清肿瘤坏死因子-α和 IL-4 浓度显著升高（P<0.05）。饲喂添加 LBP 的日粮的肉鸡血清 IL-6 和干扰素γ浓度呈线性（P<0.05）和二次曲线（P<0.05）增加。结果表明，日粮补充 LBP 可以提高肉鸡的生长性能、消化酶活性、抗氧化能力和免疫功能。综上所述，LBP 可作为肉鸡有前途的饲料添加剂，推荐肉鸡日粮中添加 2000 mg/kg LBP。
