Division of Urogynecology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, Republic of China.
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, Taiwan, Republic of China.
Sci Rep. 2020 Feb 6;10(1):1944. doi: 10.1038/s41598-020-58594-3.
Patients with pelvic organ prolapse (POP) often have accompanying lower urinary tract symptoms. Symptoms such as stress urinary incontinence(SUI-) and detrusor overactivty(DO) would co-exist in a number of patients. Management entails relieving the obstructive element. To determine the clinical outcome of patients with urodynamics mixed type urinary incontinence(MUI-U) after vaginal pelvic reconstructive surgery(PRS), a retrospective study was conducted. MUI-U was defined as having urodynamic findings of both of DO/DOI (derusor overactivity incontinence) and SUI-. Main outcome measures: Objective cure- absence of involuntary detrusor contraction on filling cystometry and no demonstrable leakage of urine during increased abdominal pressure; Subjective cure- assessment index score of <1 on UDI-6 question #2 and #3. Of the 82 patients evaluated, 14 underwent vaginal PRS with concomitant mid-urethral sling(MUS) insertion while 68 had vaginal PRS alone. Pre-operatively, 49(60%) patients had stage III and 33(40%) had stage IV prolapse. Post-operatively, 1-year data shows an objective cure of 56% (46/82) and subjective cure of 54% (44/82). MUI-U was significantly improved. Improvement of SUI and results of the 1-hour pad test were more pronounced in patients with concomitant MUS insertion. Ergo, vaginal PRS cures symptoms of MUI-U in >50% of patients and concomitant MUS can be offered to SUI predominant MUI.
患有盆腔器官脱垂(POP)的患者常伴有下尿路症状。许多患者会同时出现压力性尿失禁(SUI-)和逼尿肌过度活动(DO)等症状。治疗需要缓解阻塞因素。为了确定经阴道盆腔重建术后尿动力学混合性尿失禁(MUI-U)患者的临床结局,进行了一项回顾性研究。MUI-U 的定义为存在 DO/DOI(逼尿肌过度活动性尿失禁)和 SUI 的尿动力学发现。主要观察指标:客观治愈-充盈膀胱测压时无不自主逼尿肌收缩,增加腹压时无尿液漏出;主观治愈-UDI-6 问题 #2 和 #3 的评估指数评分<1。在评估的 82 名患者中,14 名患者接受了阴道 PRS 联合中尿道吊带(MUS)插入,68 名患者仅接受了阴道 PRS。术前,49 名(60%)患者为 III 期,33 名(40%)患者为 IV 期脱垂。术后 1 年数据显示客观治愈率为 56%(46/82),主观治愈率为 54%(44/82)。MUI-U 显著改善。在伴有 MUS 插入的患者中,SUI 的改善和 1 小时垫试验结果更为明显。因此,阴道 PRS 可治愈超过 50%的 MUI-U 患者的症状,对于以 SUI 为主的 MUI 可考虑联合 MUS。