School of Human Kinetics, Faculty of Health Science, University of Ottawa, 125 University Avenue, Ottawa, ON, K1N 6N5, Canada.
Faculty of Health Science, Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Canada.
Exp Brain Res. 2020 Mar;238(3):657-666. doi: 10.1007/s00221-020-05742-w. Epub 2020 Feb 6.
The neural mechanisms underlying movement automaticity have been investigated using PET and fMRI and more recently functional near-infrared spectroscopy (fNIRS). As fNIRS is an emerging technique, the objective of the present study was to replicate the functional magnetic resonance imaging-related motor sequence findings as reported by Wu et al. (J Neurophysiol 91:1690-1698, https://doi.org/10.1152/jn.01052.2003, 2004) using fNIRS. Seventeen right-handed participants practiced self-initiated sequential finger movements of two lengths (4 and 12) until a level of automaticity was achieved. Automaticity was evaluated by performing a visual-letter-counting task concurrently with the sequential finger movements. Our data were unable to replicate the pre-to-post-practice decrease in cortical activity in the left dorsolateral prefrontal cortex for both motor sequence tasks. The findings did reveal increased contribution from the right hemisphere following learning. The observed lateralization is suggestive of explicit learning and the involvement of working memory in motor sequence production.
运用正电子发射断层扫描（PET）和功能磁共振成像（fMRI），最近又运用近红外光谱（fNIRS），对运动自动化的神经机制进行了研究。由于 fNIRS 是一种新兴技术，本研究的目的是复制 Wu 等人报道的与功能磁共振成像相关的运动序列研究结果（J Neurophysiol 91:1690-1698，https://doi.org/10.1152/jn.01052.2003, 2004），采用 fNIRS 进行检测。17 名右利手参与者练习自主发起两种长度（4 和 12）的顺序手指运动，直到达到自动化水平。通过在进行顺序手指运动的同时执行视觉字母计数任务，来评估自动化程度。我们的数据无法复制 Wu 等人的研究结果，即在两种运动序列任务中，练习前到练习后的左背外侧前额叶皮质的皮质活动减少。研究结果确实显示，学习后右半球的贡献增加。观察到的偏侧化提示了在运动序列产生中，明确学习和工作记忆的参与。
