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超声对甲状腺髓样癌的诊断价值:与 CT 的对比研究。

The Diagnostic Value of Ultrasound in Medullary Thyroid Carcinoma: A Comparison With Computed Tomography.

机构信息

Department of Ultrasound, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820905832. doi: 10.1177/1533033820905832.

DOI:10.1177/1533033820905832
PMID:32031054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011316/
Abstract

PURPOSE

To explore the clinical value of ultrasound in the diagnosis of medullary thyroid carcinoma by comparing with enhanced computed tomography.

METHODS

This retrospective study was performed on 62 patients with pathologically confirmed medullary thyroid carcinoma. All patients underwent ultrasound and enhanced computed tomography examinations before surgery. The findings of the pathologic examination of resected specimens were considered as gold standard and were compared with the results of these 2 methods.

RESULTS

There were 73 medullary thyroid carcinoma lesions and 29 benign lesions in 62 patients. In all, 55 of 73 medullary thyroid carcinoma lesions and 27 of 29 benign lesions were correctly diagnosed by ultrasound; and 45 of 73 medullary thyroid carcinoma lesions and 24 of 29 benign lesions were correctly diagnosed by enhanced computed tomography. The accuracy of ultrasound and enhanced computed tomography was 80.4% and 67.6%, respectively. There was significant difference between 2 methods ( < .05).

CONCLUSIONS

Ultrasound can be used to observe the location, number, size, shape, border, internal echo, calcification, and blood flow of the lesion. It is a convenient, inexpensive, and nonradiative method with higher accuracy than enhanced computed tomography.

摘要

目的

通过与增强 CT 比较,探讨超声在诊断甲状腺髓样癌中的临床价值。

方法

本回顾性研究纳入了 62 例经病理证实为甲状腺髓样癌的患者。所有患者均在术前接受了超声和增强 CT 检查。以切除标本的病理检查结果为金标准,并将其与这 2 种方法的结果进行比较。

结果

在 62 例患者中,共发现 73 个甲状腺髓样癌病灶和 29 个良性病灶。超声正确诊断了 73 个甲状腺髓样癌病灶中的 55 个,正确诊断了 29 个良性病灶中的 27 个;增强 CT 正确诊断了 73 个甲状腺髓样癌病灶中的 45 个,正确诊断了 29 个良性病灶中的 24 个。超声和增强 CT 的准确率分别为 80.4%和 67.6%。2 种方法之间存在显著差异(<0.05)。

结论

超声可以观察到病变的位置、数量、大小、形状、边界、内部回声、钙化和血流情况。它是一种方便、廉价、无辐射的方法,准确率高于增强 CT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/b8370d9fc767/10.1177_1533033820905832-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/662c3674a379/10.1177_1533033820905832-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/6a78b94205c2/10.1177_1533033820905832-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/c48429988178/10.1177_1533033820905832-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/c3bf65964f6f/10.1177_1533033820905832-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/b8370d9fc767/10.1177_1533033820905832-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/662c3674a379/10.1177_1533033820905832-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/6a78b94205c2/10.1177_1533033820905832-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/c48429988178/10.1177_1533033820905832-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/c3bf65964f6f/10.1177_1533033820905832-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/259f/7011316/b8370d9fc767/10.1177_1533033820905832-fig5.jpg

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本文引用的文献

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Oncotarget. 2017 Apr 18;8(16):27520-27528. doi: 10.18632/oncotarget.15897.
2
Hypervascularity is more frequent in medullary thyroid carcinoma: Compared with papillary thyroid carcinoma.髓样甲状腺癌的血管增多比乳头状甲状腺癌更常见。 与乳头状甲状腺癌相比。
Medicine (Baltimore). 2016 Dec;95(49):e5502. doi: 10.1097/MD.0000000000005502.
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AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ASSOCIAZIONE MEDICI ENDOCRINOLOGI MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES--2016 UPDATE.
使用术前超声血管特征来评估甲状腺髓样癌。
Cancer Imaging. 2023 Jun 20;23(1):64. doi: 10.1186/s40644-023-00583-6.
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Update on the Diagnosis and Management of Medullary Thyroid Cancer: What Has Changed in Recent Years?甲状腺髓样癌诊断与管理的最新进展:近年来有哪些变化?
Cancers (Basel). 2022 Jul 27;14(15):3643. doi: 10.3390/cancers14153643.
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Suboptimal accuracy of ultrasound and ultrasound-based risk stratification systems in detecting medullary thyroid carcinoma should not be overlooked. Findings from a systematic review with meta-analysis.超声和基于超声的风险分层系统在检测甲状腺髓样癌方面的准确性不够理想,这一点不应被忽视。系统评价和荟萃分析的结果。
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