Mondal Anindita, Das Mou, Chatterjee Uttara, Datta Chhanda
Department of Pathology, IPGME and R, Kolkata, West Bengal, India.
Indian J Pathol Microbiol. 2020 Jan-Mar;63(1):122-124. doi: 10.4103/IJPM.IJPM_237_19.
Retiform hemangioendothelioma is a rare vascular neoplasm of intermediate grade, the diagnosis of which can be challenging. We report a case of 35-year-old man with swelling in the postauricular region. He had undergone FNAC which had revealed blood only. Microscopic examination showed narrow, arborizing, vascular channels resembling normal rete testis. Evidence of mitoses or cytological atypia were lacking. Immunohistochemistry showed diffuse and strong staining for CD34 along with CD31 positivity. Immunostains for D240 and GLUT1 were negative. A diagnosis of retiform hemangioendothelioma was made. Histologically, it should be distinguished from Kaposiform hemangioendothelioma, Dabska tumor, epithelioid hemangioendothelioma, and angiosarcoma.
网状血管内皮瘤是一种罕见的中等分级血管肿瘤，其诊断具有挑战性。我们报告一例35岁男性耳后区域肿胀的病例。他接受了细针穿刺抽吸活检，结果仅显示有血液。显微镜检查显示狭窄、呈树枝状的血管通道，类似正常睾丸网。未见有丝分裂或细胞学异型性证据。免疫组化显示CD34弥漫性强染色，同时CD31阳性。D240和GLUT1免疫染色阴性。诊断为网状血管内皮瘤。在组织学上，它应与卡波西样血管内皮瘤、达布斯卡瘤、上皮样血管内皮瘤和血管肉瘤相鉴别。
