Parween Shagufta, George Joann Pauline, Prabhuji Mlv
Int J Periodontics Restorative Dent. 2020 Mar/Apr;40(2):e43-e51. doi: 10.11607/prd.4505.
The aim of this randomized controlled trial was to compare the clinical outcomes of modified coronally advanced tunnel technique (MCAT) with subepithelial connective tissue graft (SCTG) with and without recombinant human platelet-derived growth factor-BB (rhPDGF-BB) for mandibular multiple recessions. Twenty-four Miller Class I and III recessions were randomly assigned to a group: test (MCAT+SCTG+rhPDGF-BB) or control (MCAT+SCTG). After 6 months, mean recession-depth reduction was higher in the test group (2.08 ± 0.90 mm) than the control (1.83 ± 0.93 mm). Mean root coverage was achieved, favoring the test group (82.6% ± 23.69%) instead of the control (56.2% ± 28.55%). Complete root coverage for the test group was 58.3%, which was significantly superior to control (16.7%). The use of rhPDGF-BB+SCTG using MCAT offered an advantage of a minimally invasive, predictable method for achieving optimal outcomes.
这项随机对照试验的目的是比较改良冠状推进隧道技术（MCAT）联合上皮下结缔组织移植（SCTG），以及联合或不联合重组人血小板衍生生长因子-BB（rhPDGF-BB）治疗下颌多处牙龈退缩的临床效果。将24例米勒I类和III类牙龈退缩随机分为两组：试验组（MCAT+SCTG+rhPDGF-BB）和对照组（MCAT+SCTG）。6个月后，试验组的平均牙龈退缩深度减少量（2.08±0.90mm）高于对照组（1.83±0.93mm）。平均牙根覆盖情况有利于试验组（82.6%±23.69%）而非对照组（56.2%±28.55%）。试验组的完全牙根覆盖率为58.3%，显著优于对照组（16.7%）。采用MCAT联合rhPDGF-BB+SCTG提供了一种微创、可预测的方法来实现最佳治疗效果。
