• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用带自体移植或聚合物替代物的冠向推进瓣或隧道技术治疗牙龈退缩:一项系统评价和荟萃分析

Treating Gingival Recessions Using Coronally Advanced Flap or Tunnel Techniques with Autografts or Polymeric Substitutes: A Systematic Review and Meta-Analysis.

作者信息

Toledano-Osorio Manuel, Muñoz-Soto Esther, Toledano Manuel, Vallecillo-Rivas Marta, Vallecillo Cristina, Ramos-García Pablo, Osorio Raquel

机构信息

Faculty of Dentistry, Colegio Máximo de Cartuja s/n, University of Granada, 18071 Granada, Spain.

出版信息

Polymers (Basel). 2022 Apr 2;14(7):1453. doi: 10.3390/polym14071453.

DOI:10.3390/polym14071453
PMID:35406326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9002830/
Abstract

Gingival recessions are a prevalent oral mucosa alteration. To solve this pathology, palatal mucosa or polymeric soft tissue substitutes are used when performing coronal advanced flap (CAF) or tunnel (TUN) surgical techniques. To evaluate which is the most successful approach, a literature review and meta-analysis were conducted. For the electronic search the National Library of Medicine, the Cochrane Oral Health Group Trials Register, EMBASE and WOS were used. Pooled data for the percentage of root coverage was collected and weighted means were calculated. Heterogeneity was determined using the Higgins (I) statistic and a random-effects model was applied. Thirteen studies were included in the systematic review (12 randomized and 1 controlled clinical trials) in which both techniques (394 patients) were compared with a follow-up of 4 to 12 months. Galbraith and Baujat plots were used to control for the presence of potential outliers. After performing the meta-analysis (11 studies), the mean root coverage was similar when using the TUN or CAF techniques ( = 0.49). The only differences between the two were found for single recessions, where CAF offered a higher percentage of root coverage (mean difference = 4.98%; = 0.006). There were no differences when applying an autograft or a polymeric substitute with either of the two tested surgical techniques ( = 0.445).

摘要

牙龈退缩是一种常见的口腔黏膜改变。为了解决这一病理问题,在进行冠向推进瓣(CAF)或隧道(TUN)手术技术时,会使用腭黏膜或聚合物软组织替代物。为了评估哪种方法最成功,进行了一项文献综述和荟萃分析。电子检索使用了美国国立医学图书馆、Cochrane口腔健康组试验注册库、EMBASE和WOS。收集了牙根覆盖百分比的汇总数据并计算加权均值。使用希金斯(I)统计量确定异质性,并应用随机效应模型。系统评价纳入了13项研究(12项随机对照试验和1项对照临床试验),对两种技术(394例患者)进行了比较,随访时间为4至12个月。使用加尔布雷思图和鲍亚特图来控制潜在异常值的存在。进行荟萃分析(11项研究)后,使用TUN或CAF技术时的平均牙根覆盖相似( = 0.49)。两者之间的唯一差异在于单个退缩情况,CAF的牙根覆盖百分比更高(平均差异 = 4.98%; = 0.006)。在两种测试手术技术中应用自体移植物或聚合物替代物时没有差异( = 0.445)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/8000f0d82392/polymers-14-01453-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/29b7c9304ae5/polymers-14-01453-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/bcc70c5b0c9b/polymers-14-01453-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/2627a30a6e6f/polymers-14-01453-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/b4d6568ce3e5/polymers-14-01453-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/5d45e9d6c9c3/polymers-14-01453-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/41b9a113f594/polymers-14-01453-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/471c439cd006/polymers-14-01453-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/d716a533a7a3/polymers-14-01453-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/ed3a282e7271/polymers-14-01453-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/8000f0d82392/polymers-14-01453-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/29b7c9304ae5/polymers-14-01453-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/bcc70c5b0c9b/polymers-14-01453-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/2627a30a6e6f/polymers-14-01453-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/b4d6568ce3e5/polymers-14-01453-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/5d45e9d6c9c3/polymers-14-01453-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/41b9a113f594/polymers-14-01453-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/471c439cd006/polymers-14-01453-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/d716a533a7a3/polymers-14-01453-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/ed3a282e7271/polymers-14-01453-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/9002830/8000f0d82392/polymers-14-01453-g010.jpg

相似文献

1
Treating Gingival Recessions Using Coronally Advanced Flap or Tunnel Techniques with Autografts or Polymeric Substitutes: A Systematic Review and Meta-Analysis.使用带自体移植或聚合物替代物的冠向推进瓣或隧道技术治疗牙龈退缩:一项系统评价和荟萃分析
Polymers (Basel). 2022 Apr 2;14(7):1453. doi: 10.3390/polym14071453.
2
Efficacy of tunnel technique in the treatment of localized and multiple gingival recessions: A systematic review and meta-analysis.隧道技术治疗局限性和多发性牙龈退缩的疗效:系统评价和荟萃分析。
J Periodontol. 2018 Sep;89(9):1075-1090. doi: 10.1002/JPER.18-0066. Epub 2018 Aug 13.
3
Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivate for root coverage: 5-year results of an RCT using 3D digital measurement technology for volumetric comparison of soft tissue changes.隧道技术联合结缔组织移植与冠向复位瓣联合 enamel matrix derivate 用于根面覆盖:5 年 RCT 结果,采用 3D 数字测量技术对软组织变化的体积进行比较。
J Clin Periodontol. 2021 Jul;48(7):949-961. doi: 10.1111/jcpe.13470. Epub 2021 May 4.
4
Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivative for root coverage: a RCT using 3D digital measuring methods. Part II. Volumetric studies on healing dynamics and gingival dimensions.采用结缔组织移植的隧道技术与应用釉基质衍生物的冠向复位瓣用于牙根覆盖的比较:一项使用三维数字测量方法的随机对照试验。第二部分。愈合动态及牙龈维度的体积研究
J Clin Periodontol. 2014 Jun;41(6):593-603. doi: 10.1111/jcpe.12254.
5
Tunnel technique versus coronally advanced flap with acellular dermal matrix graft in the treatment of multiple gingival recessions.隧道技术与带acellular dermal matrix graft 的冠向推进瓣在治疗多个牙龈退缩中的应用比较。
J Clin Periodontol. 2015 Dec;42(12):1135-42. doi: 10.1111/jcpe.12477. Epub 2016 Jan 8.
6
Periosteal pedicle graft with coronally advanced flap and its comparison with modified coronally advanced flap in the treatment of multiple adjacent gingival recessions-a randomized clinical trial.带骨膜蒂移植术联合冠向复位瓣及其与改良冠向复位瓣治疗多个相邻牙龈退缩的比较——一项随机临床试验
J Oral Biol Craniofac Res. 2021 Apr-Jun;11(2):99-106. doi: 10.1016/j.jobcr.2020.12.003. Epub 2021 Jan 6.
7
Platelet-Rich Fibrin in Single and Multiple Coronally Advanced Flap for Type 1 Recession: An Updated Systematic Review and Meta-Analysis.富含血小板纤维蛋白在单瓣和多瓣冠向推进瓣治疗1型牙龈退缩中的应用:一项更新的系统评价和荟萃分析。
Medicina (Kaunas). 2021 Feb 5;57(2):144. doi: 10.3390/medicina57020144.
8
Efficacy of xenogeneic collagen matrix in the treatment of gingival recessions: A systematic review and meta-analysis.异种胶原基质治疗牙龈退缩的疗效:系统评价和荟萃分析。
Oral Dis. 2019 May;25(4):996-1008. doi: 10.1111/odi.12949. Epub 2018 Aug 28.
9
Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivative for root coverage: a RCT using 3D digital measuring methods. Part I. Clinical and patient-centred outcomes.结缔组织移植隧道技术与应用釉基质衍生物的冠向推进瓣用于牙根覆盖的比较:一项采用三维数字测量方法的随机对照试验。第一部分。临床和以患者为中心的结果。
J Clin Periodontol. 2014 Jun;41(6):582-92. doi: 10.1111/jcpe.12178. Epub 2013 Nov 10.
10
Effectiveness of connective tissue graft substitutes for the treatment of gingival recessions compared with coronally advanced flap: a network meta-analysis.结缔组织移植物替代品治疗牙龈退缩与冠向复位瓣的疗效比较:网状荟萃分析。
Clin Oral Investig. 2020 Oct;24(10):3395-3406. doi: 10.1007/s00784-020-03547-3. Epub 2020 Aug 26.

引用本文的文献

1
Clinical efficacy of tunnel flap combined with de-epithelialized connective tissue graft in treating gingival recession: a case-series study.隧道瓣联合去上皮结缔组织移植治疗牙龈退缩的临床疗效:一项病例系列研究。
Odontology. 2025 Apr 13. doi: 10.1007/s10266-025-01100-w.
2
Collagen Matrix Versus Subepithelial Connective Tissue for Recession Coverage: A Systematic Review.用于退缩覆盖的胶原基质与上皮下结缔组织:一项系统评价。
Oral Dis. 2025 Apr;31(4):1092-1106. doi: 10.1111/odi.15203. Epub 2024 Dec 9.
3
Management of Soft Tissue Defects Around Single Implants: A Systematic Review of the Literature.

本文引用的文献

1
Root coverage with tunneling technique or modified advanced flap associated with acellular dermal matrix: results from 6 months randomized clinical trial.采用隧道技术或改良的改良高级瓣联合脱细胞真皮基质进行牙根覆盖:6个月随机临床试验结果
Clin Oral Investig. 2022 Jan;26(1):773-780. doi: 10.1007/s00784-021-04055-8. Epub 2021 Aug 7.
2
Collagen Matrix vs. Autogenous Connective Tissue Graft for Soft Tissue Augmentation: A Systematic Review and Meta-Analysis.用于软组织增量的胶原基质与自体结缔组织移植:一项系统评价与荟萃分析
Polymers (Basel). 2021 May 31;13(11):1810. doi: 10.3390/polym13111810.
3
Treatment of Gingival Recession: When and How?
单颗种植体周围软组织缺损的处理:文献系统回顾
Clin Exp Dent Res. 2024 Dec;10(6):e70003. doi: 10.1002/cre2.70003.
4
Mixed-Thickness Tunnel Access (MiTT) through a Linear Vertical Mucosal Incision for a Minimally Invasive Approach for Root Coverage Procedures in Anterior and Posterior Sites: Technical Description and Case Series with 1-Year Follow-Up.通过线性垂直黏膜切口的混合厚度隧道入路(MiTT)用于前牙和后牙区根面覆盖手术的微创方法:技术描述及1年随访的病例系列
Dent J (Basel). 2023 Oct 7;11(10):235. doi: 10.3390/dj11100235.
5
Allogenic Acellular Dermal Matrix and Xenogeneic Dermal Matrix as Connective Tissue Graft Substitutes for Long-Term Stability Gingival Recession Therapy: A Systematic Review and Meta-Analysis.同种异体脱细胞真皮基质和异种真皮基质作为结缔组织移植替代物用于长期稳定性牙龈退缩治疗:一项系统评价和荟萃分析。
Eur J Dent. 2024 May;18(2):430-440. doi: 10.1055/s-0043-1772778. Epub 2023 Oct 17.
6
Spatio-temporal disparities of Clonorchis sinensis infection in animal hosts in China: a systematic review and meta-analysis.中国动物宿主华支睾吸虫感染的时空差异:系统评价和荟萃分析。
Infect Dis Poverty. 2023 Oct 17;12(1):97. doi: 10.1186/s40249-023-01146-4.
7
Comparison of the efficacy and long-term stability of tunnel technique and coronally advanced flap in the treatment of gingival recession: a Meta-analysis.隧道技术与冠向复位瓣术治疗牙龈退缩的疗效及长期稳定性比较:Meta 分析。
Hua Xi Kou Qiang Yi Xue Za Zhi. 2023 Aug 1;41(4):450-462. doi: 10.7518/hxkq.2023.2023045.
8
Clinical Evaluation of Bilateral Multiple Gingival Recession Treatment with Autogenous Connective Tissue Graft Associated with Low-Level Laser Therapy.自体结缔组织移植联合低强度激光治疗双侧多发性牙龈退缩的临床评估
J Clin Med. 2023 Mar 17;12(6):2349. doi: 10.3390/jcm12062349.
9
Influence of graft thickness on tunnel technique procedures for root coverage: a pilot split-mouth randomized controlled trial.移植物厚度对根覆盖隧道技术操作的影响:一项前瞻性半口随机对照试验。
Clin Oral Investig. 2023 Jul;27(7):3469-3477. doi: 10.1007/s00784-023-04955-x. Epub 2023 Mar 21.
牙龈退缩的治疗:何时及如何治疗?
Int Dent J. 2021 Jun;71(3):178-187. doi: 10.1111/idj.12617. Epub 2021 Jan 29.
4
Efficacy of microsurgery and comparison to macrosurgery for gingival recession treatment: a systematic review with meta-analysis.微创与宏观手术治疗牙龈退缩的疗效比较:系统评价与荟萃分析。
Clin Oral Investig. 2021 Jul;25(7):4269-4280. doi: 10.1007/s00784-021-03954-0. Epub 2021 Apr 29.
5
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis.使用聚合物膜进行牙槽嵴增高术:一项系统评价与Meta分析
Polymers (Basel). 2021 Apr 6;13(7):1172. doi: 10.3390/polym13071172.
6
Efficacy of modified coronally advanced flap in the treatment of multiple adjacent gingival recessions: a systematic review and meta-analysis.改良冠向推进瓣术治疗多个相邻牙龈退缩的疗效:系统评价和荟萃分析。
Acta Odontol Scand. 2021 Nov;79(8):562-572. doi: 10.1080/00016357.2021.1908594. Epub 2021 Apr 26.
7
Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivate for root coverage: 5-year results of an RCT using 3D digital measurement technology for volumetric comparison of soft tissue changes.隧道技术联合结缔组织移植与冠向复位瓣联合 enamel matrix derivate 用于根面覆盖:5 年 RCT 结果,采用 3D 数字测量技术对软组织变化的体积进行比较。
J Clin Periodontol. 2021 Jul;48(7):949-961. doi: 10.1111/jcpe.13470. Epub 2021 May 4.
8
Regenerative Potential of Enamel Matrix Protein Derivative and Acellular Dermal Matrix for Gingival Recession: A Systematic Review and Meta-Analysis.牙釉质基质蛋白衍生物与脱细胞真皮基质治疗牙龈退缩的再生潜力:一项系统评价与Meta分析
Proteomes. 2021 Feb 25;9(1):11. doi: 10.3390/proteomes9010011.
9
Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review.胶原生物基质治疗牙龈退缩的当前见解:一项基于证据的系统评价
Polymers (Basel). 2020 Sep 13;12(9):2081. doi: 10.3390/polym12092081.
10
State of the Art on Biomaterials for Soft Tissue Augmentation in the Oral Cavity. Part II: Synthetic Polymers-Based Biomaterials.口腔软组织增量生物材料的研究现状。第二部分:合成聚合物基生物材料。
Polymers (Basel). 2020 Aug 17;12(8):1845. doi: 10.3390/polym12081845.