子宫内膜间质肉瘤中的10号与19号染色体易位。

Ins(10;19) in an endometrial stromal sarcoma.

作者信息

Dal Cin P, Talcott J, Abrams J, Li F P, Sandberg A A

机构信息

Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.

出版信息

Cancer Genet Cytogenet. 1988 Nov;36(1):1-5. doi: 10.1016/0165-4608(88)90068-4.

DOI:10.1016/0165-4608(88)90068-4

PMID:3203291

Abstract

A 37-year-old woman with a history of bilateral mesenchymal cystic hamartomata of the lung was subsequently found to have low-grade endometrial stromal sarcoma. Cytogenetic analysis of the uterine tumor revealed, in all metaphases, an unusual derivative chromosome generated by the insertion of chromosome 19 into chromosome 10 at the level of its centromere [ins(10;19)(p11;p13q13)].

摘要

一名37岁有双侧肺间叶性囊性错构瘤病史的女性，随后被发现患有低级别子宫内膜间质肉瘤。对子宫肿瘤进行的细胞遗传学分析显示，在所有中期相中，均出现一条异常的衍生染色体，该染色体由19号染色体插入10号染色体着丝粒水平处形成[插入(10;19)(p11;p13q13)]。